@article{https://authors.library.caltech.edu/records/zks5d-wkw57, title = "Single-tissue proteomics in Caenorhabditis elegans reveals proteins resident in intestinal lysosome-related organelles", journal = "Proceedings of the National Academy of Sciences", year = "2024", url = "https://authors.library.caltech.edu/records/zks5d-wkw57", id = "record", issn = "0027-8424", doi = "10.1073/pnas.2322588121", volume = "121" } @article{https://authors.library.caltech.edu/records/x44fc-kq819, title = "Increasing Proteome Coverage Through a Reduction in Analyte Complexity in Single-Cell Equivalent Samples", journal = "Journal of Proteome Research", year = "2024", url = "https://authors.library.caltech.edu/records/x44fc-kq819", id = "record", issn = "1535-3893", doi = "10.1021/acs.jproteome.4c00062" } @article{https://authors.library.caltech.edu/records/p2w5p-g5v97, title = "Exploring in vivo combinatorial chemo-immunotherapy: Addressing p97 suppression and immune reinvigoration in pancreatic cancer with tumor microenvironment-responsive nanoformulation", journal = "Biomedicine \& Pharmacotherapy", year = "2024", url = "https://authors.library.caltech.edu/records/p2w5p-g5v97", id = "record", issn = "0753-3322", doi = "10.1016/j.biopha.2024.116660", volume = "175" } @article{https://authors.library.caltech.edu/records/0n9mw-3zh77, title = "AI is a viable alternative to high throughput screening: a 318-target study", journal = "Scientific Reports", year = "2024", url = "https://authors.library.caltech.edu/records/0n9mw-3zh77", id = "record", issn = "2045-2322", doi = "10.1038/s41598-024-54655-z", volume = "14" } @article{https://authors.library.caltech.edu/records/3sf7s-k5f89, title = "An innovative nanoformulation utilizing tumor microenvironment-responsive PEG-polyglutamic coating and dynamic charge adjustment for specific targeting of ER stress inducer, microRNA, and immunoadjuvant in pancreatic cancer: In vitro investigations", journal = "International Journal of Biological Macromolecules", year = "2024", url = "https://authors.library.caltech.edu/records/3sf7s-k5f89", id = "record", issn = "0141-8130", doi = "10.1016/j.ijbiomac.2023.127905", volume = "254" } @article{https://authors.library.caltech.edu/records/0kd3x-c9h52, title = "An autosomal-dominant childhood-onset disorder associated with pathogenic variants in VCP", journal = "American Journal of Human Genetics", year = "2023", url = "https://authors.library.caltech.edu/records/0kd3x-c9h52", id = "record", issn = "0002-9297", volume = "110", pmcid = "PMC10645565" } @article{https://authors.library.caltech.edu/records/25eyv-y8h36, title = "Impact of Germline Depletion of Bonus on Chromatin State in Drosophila Ovaries", journal = "Cells", year = "2023", url = "https://authors.library.caltech.edu/records/25eyv-y8h36", id = "record", issn = "2073-4409", doi = "10.3390/cells12222629", volume = "12", pmcid = "PMC10670193" } @article{https://authors.library.caltech.edu/records/ryb4b-15p31, title = "Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer", journal = "Science Advances", year = "2023", url = "https://authors.library.caltech.edu/records/ryb4b-15p31", id = "record", issn = "2375-2548", doi = "10.1126/sciadv.ade3816", volume = "9", pmcid = "PMC10575592" } @article{https://authors.library.caltech.edu/records/ed76t-rjk79, title = "Clinical Classification of Variants in the Valosin-Containing Protein Gene Associated With Multisystem Proteinopathy", journal = "Neurology Genetics", year = "2023", url = "https://authors.library.caltech.edu/records/ed76t-rjk79", id = "record", issn = "2376-7839", doi = "10.1212/nxg.0000000000200093", volume = "9" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230628-295410000.8, title = "A wireless patch for the monitoring of C-reactive protein in sweat", journal = "Nature Biomedical Engineering", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230628-295410000.8", id = "record", issn = "2157-846X", doi = "10.1038/s41551-023-01059-5", volume = "7", pmcid = "PMC10592261" } @article{https://authors.library.caltech.edu/records/d9008-tnp79, title = "Skeletal muscle cell protein dysregulation highlights the pathogenesis mechanism of myopathy-associated p97/VCP R155H mutations", journal = "Frontiers in Neurology", year = "2023", url = "https://authors.library.caltech.edu/records/d9008-tnp79", id = "record", issn = "1664-2295", volume = "14", pmcid = "PMC10435852" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230711-988768900.15, title = "Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer", journal = "ACS Medicinal Chemistry Letters", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230711-988768900.15", id = "record", issn = "1948-5875", doi = "10.1021/acsmedchemlett.3c00163", volume = "14", pmcid = "PMC10351062" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230628-257129000.25, title = "DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1", journal = "Molecular Therapy - Nucleic Acids", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230628-257129000.25", id = "record", issn = "2162-2531", doi = "10.1016/j.omtn.2023.05.017", volume = "32", pmcid = "PMC10280091" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230615-129123000.8, title = "Tidyproteomics: an open-source R package and data object for quantitative proteomics post analysis and visualization", journal = "BMC Bioinformatics", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230615-129123000.8", id = "record", issn = "1471-2105", doi = "10.1186/s12859-023-05360-7", volume = "24", pmcid = "PMC10246047" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230628-257245000.39, title = "Structure of Anabaena flos-aquae gas vesicles revealed by cryo-ET", journal = "Structure", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230628-257245000.39", id = "record", issn = "0969-2126", doi = "10.1016/j.str.2023.03.011", volume = "31", pmcid = "PMC10185304" } @article{https://authors.library.caltech.edu/records/j5hz6-v6q90, title = "TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1", journal = "Molecular Cell", year = "2023", url = "https://authors.library.caltech.edu/records/j5hz6-v6q90", id = "record", issn = "1097-2765", doi = "10.1016/j.molcel.2023.02.023", volume = "83", pmcid = "PMC10112281" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230228-36558000.1, title = "MTCH2 is a mitochondrial outer membrane protein insertase", journal = "Science", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230228-36558000.1", id = "record", issn = "0036-8075", doi = "10.1126/science.add1856", volume = "378", pmcid = "PMC9674023" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221019-343672700.6, title = "Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria", journal = "Nature Communications", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221019-343672700.6", id = "record", issn = "2041-1723", doi = "10.1038/s41467-022-33505-4", volume = "13", pmcid = "PMC9529944" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221107-998820100.20, title = "Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs", journal = "Molecular Cancer Therapeutics", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221107-998820100.20", id = "record", issn = "1535-7163", doi = "10.1158/1535-7163.mct-22-0167", volume = "21", pmcid = "PMC9538592" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220808-223822000, title = "Mechanisms of chlorate toxicity and resistance in Pseudomonas aeruginosa", journal = "Molecular Microbiology", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220808-223822000", id = "record", issn = "0950-382X", doi = "10.1111/mmi.14972", volume = "118", pmcid = "PMC9589919" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220603-698843600, title = "Surface cysteines could protect the SARS-CoV-2 main protease from oxidative damage", journal = "Journal of Inorganic Biochemistry", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220603-698843600", id = "record", issn = "0162-0134", doi = "10.1016/j.jinorgbio.2022.111886", volume = "234", pmcid = "PMC9161685" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220816-373597000, title = "System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity", journal = "iScience", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220816-373597000", id = "record", issn = "2589-0042", doi = "10.1016/j.isci.2022.104756", volume = "25", pmcid = "PMC9356101" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220722-768560000, title = "P97/VCP ATPase inhibitors can rescue p97 mutation-linked motor neuron degeneration", journal = "Brain Communications", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220722-768560000", id = "record", issn = "2632-1297", doi = "10.1093/braincomms/fcac176", volume = "4", pmcid = "PMC9294923" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220708-104460300, title = "Sulforaphane is Synergistic with CB‐5083 and Inhibits Colony Formation of CB‐5083‐Resistant HCT116 Cells", journal = "ChemMedChem", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220708-104460300", id = "record", issn = "1860-7179", doi = "10.1002/cmdc.202200030", volume = "17" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220329-753949840, title = "Discovery of small-molecule inhibitors of RUVBL1/2 ATPase", journal = "Bioorganic and Medicinal Chemistry", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220329-753949840", id = "record", issn = "0968-0896", doi = "10.1016/j.bmc.2022.116726", volume = "62", pmcid = "PMC9034851" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220429-183149900, title = "NMS-873 Leads to Dysfunctional Glycometabolism in A p97-Independent Manner in HCT116 Colon Cancer Cells", journal = "Pharmaceutics", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220429-183149900", id = "record", issn = "1999-4923", doi = "10.3390/pharmaceutics14040764", volume = "14", pmcid = "PMC9024726" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20211201-482793884, title = "Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition", journal = "Cell Chemical Biology", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211201-482793884", id = "record", issn = "2451-9456", doi = "10.1016/j.chembiol.2021.11.005", volume = "29", pmcid = "PMC8934257" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220422-231850720, title = "Mechanism of the alteration in domain-domain communications in human p97/VCP atpase", journal = "Biophysical Journal", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220422-231850720", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2021.11.1259", volume = "121" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220208-948531000, title = "The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation", journal = "Pharmaceuticals", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220208-948531000", id = "record", issn = "1424-8247", doi = "10.3390/ph15020204", volume = "15", pmcid = "PMC8880557" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210528-084342141, title = "The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection", journal = "mBio", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210528-084342141", id = "record", issn = "2150-7511", doi = "10.1128/mBio.02716-21", volume = "12", pmcid = "PMC8561387" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20211117-180505059, title = "Impacts of p97 on Proteome Changes in Human Cells during Coronaviral Replication", journal = "Cells", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211117-180505059", id = "record", issn = "2073-4409", doi = "10.3390/cells10112953", volume = "10", pmcid = "PMC8616207" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210910-171152306, title = "Conserved L464 in p97 D1–D2 linker is critical for p97 cofactor regulated ATPase activity", journal = "Biochemical Journal", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210910-171152306", id = "record", issn = "0264-6021", doi = "10.1042/bcj20210288", volume = "478", pmcid = "PMC9041309" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210518-092014570, title = "Amino Acid Analog Induces Stress Response in Marine Synechococcus", journal = "Applied and Environmental Microbiology", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210518-092014570", id = "record", issn = "0099-2240", doi = "10.1128/aem.00200-21", volume = "87" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210820-234106808, title = "Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes", journal = "International Journal of Molecular Sciences", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210820-234106808", id = "record", issn = "1422-0067", doi = "10.3390/ijms22158079", volume = "22", pmcid = "PMC8347982" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210811-212815828, title = "Neuronal VCP loss of function recapitulates FTLD-TDP pathology", journal = "Cell Reports", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210811-212815828", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2021.109399", volume = "36", pmcid = "PMC8383344" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210413-071559531, title = "AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors", journal = "European Journal of Medicinal Chemistry", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210413-071559531", id = "record", issn = "0223-5234", doi = "10.1016/j.ejmech.2021.113446", volume = "219", pmcid = "PMC8165034" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210630-194140069, title = "A GH89 human α-N-acetylglucosaminidase (hNAGLU) homologue from gut microbe Bacteroides thetaiotaomicron capable of hydrolyzing heparosan oligosaccharides", journal = "AMB Express", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210630-194140069", id = "record", issn = "2191-0855", doi = "10.1186/s13568-021-01253-1", volume = "11", pmcid = "PMC8225759" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210723-172036186, title = "Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells", journal = "Biochemical Journal", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210723-172036186", id = "record", issn = "0264-6021", doi = "10.1042/bcj20210015", volume = "478", pmcid = "PMC9074758" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210104-164231600, title = "A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells", journal = "European Journal of Medicinal Chemistry", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210104-164231600", id = "record", issn = "0223-5234", doi = "10.1016/j.ejmech.2020.113148", volume = "213", pmcid = "PMC7954469" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201215-141038657, title = "Enzyme Replacement Therapy for Mucopolysaccharidosis IIID using Recombinant Human α-N-Acetylglucosamine-6-Sulfatase in Neonatal Mice", journal = "Molecular Pharmaceutics", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201215-141038657", id = "record", issn = "1543-8384", doi = "10.1021/acs.molpharmaceut.0c00831", volume = "18", pmcid = "PMC8362844" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200727-084934912, title = "N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells", journal = "Scientific Reports", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200727-084934912", id = "record", issn = "2045-2322", doi = "10.1038/s41598-020-68615-w", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200316-130434745, title = "Allosteric p97 inhibitors can overcome resistance to ATP-competitive p97 inhibitors for potential anti-cancer therapy", journal = "ChemMedChem", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200316-130434745", id = "record", issn = "1860-7179", doi = "10.1002/cmdc.201900722", volume = "15", pmcid = "PMC9049325" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180823-134532623, title = "Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11", journal = "Cell Chemical Biology", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180823-134532623", id = "record", issn = "2451-9456", doi = "10.1016/j.chembiol.2018.07.012", volume = "25", pmcid = "PMC6309308" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565669000, title = "Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97", journal = "ACS Medicinal Chemistry Letters", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565669000", id = "record", issn = "1948-5875", doi = "10.1021/acsmedchemlett.8b00372", volume = "9", pmcid = "PMC6231190" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565878000, title = "Efficacy of Asparaginase Erwinia chrysanthemi With and Without Temozolomide Against Glioma Cells and Intracranial Mouse Medulloblastoma", journal = "Anticancer Research", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565878000", id = "record", issn = "0250-7005", doi = "10.21873/anticanres.12504", volume = "38" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171128-081216731, title = "Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway", journal = "Structure", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171128-081216731", id = "record", issn = "0969-2126", doi = "10.1016/j.str.2017.10.007", volume = "25" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565541000, title = "Specific mutations in the D1–D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors", journal = "Cell Death Discovery", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565541000", id = "record", issn = "2058-7716", doi = "10.1038/cddiscovery.2017.65", volume = "3", pmcid = "PMC5672561" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565416000, title = "Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation", journal = "PLoS ONE", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565416000", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0186818", volume = "12", pmcid = "PMC5658089" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565997000, title = "Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain", journal = "Biochemical and Biophysical Research Communications", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565997000", id = "record", issn = "0006-291X", doi = "10.1016/j.bbrc.2017.07.111", volume = "491" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565886000, title = "Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination", journal = "Cell Reports", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565886000", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2017.03.030", volume = "19", pmcid = "PMC5395095" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-564837000, title = "A structure- and chemical genomics-based approach for repositioning of drugs against VCP/p97 ATPase", journal = "Scientific Reports", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-564837000", id = "record", issn = "2045-2322", doi = "10.1038/srep44912", volume = "7", pmcid = "PMC5359624" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170324-090339100, title = "Discovery of an Inhibitor of the Proteasome Subunit Rpn11", journal = "Journal of Medicinal Chemistry", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170324-090339100", id = "record", issn = "0022-2623", doi = "10.1021/acs.jmedchem.6b01379", volume = "60", pmcid = "PMC5761724" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565696000, title = "p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein–Protein Interactions", journal = "ACS Chemical Biology", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565696000", id = "record", issn = "1554-8929", doi = "10.1021/acschembio.6b00350", volume = "11", pmcid = "PMC5224236" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565507000, title = "Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes", journal = "ChemMedChem", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565507000", id = "record", issn = "1860-7179", doi = "10.1002/cmdc.201600036", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565404000, title = "Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine", journal = "PLOS Pathogens", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565404000", id = "record", issn = "1553-7374", doi = "10.1371/journal.ppat.1004842", volume = "11", pmcid = "PMC4431732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150318-093025125, title = "Altered cofactor regulation with disease-associated p97/VCP mutations", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150318-093025125", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1418820112", volume = "112", pmcid = "PMC4394316" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565912000, title = "Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis", journal = "Neuromuscular Disorders", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565912000", id = "record", issn = "0960-8966", doi = "10.1016/j.nmd.2014.12.009", volume = "25" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565866000, title = "Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation", journal = "Case Reports in Genetics", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565866000", id = "record", issn = "2090-6544", doi = "10.1155/2015/239167", volume = "2015", pmcid = "PMC4386706" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565532000, title = "Evaluating p97 Inhibitor Analogues for Their Domain Selectivity and Potency against the p97-p47 Complex", journal = "ChemMedChem", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565532000", id = "record", issn = "1860-7179", doi = "10.1002/cmdc.201402420", volume = "10", pmcid = "PMC4280364" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141204-125558317, title = "LINKIN, a new transmembrane protein necessary for cell adhesion", journal = "eLife", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141204-125558317", id = "record", issn = "2050-084X", doi = "10.7554/eLife.04449", volume = "2014", pmcid = "PMC4275582" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565646000, title = "A novel mutation in VCP causes Charcot–Marie–Tooth Type 2 disease", journal = "Brain", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565646000", id = "record", issn = "1460-2156", doi = "10.1093/brain/awu224", volume = "137", pmcid = "PMC4208462" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140904-122954030, title = "Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140904-122954030", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1414748111", volume = "111", pmcid = "PMC4169931" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140609-114312310, title = "Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase domains", journal = "Journal of Molecular Biology", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140609-114312310", id = "record", issn = "0022-2836", doi = "10.1016/j.jmb.2014.05.022", volume = "426", pmcid = "PMC4102644" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150205-100227097, title = "Exploiting protein homeostasis for cancer therapy", journal = "FASEB Journal", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150205-100227097", id = "record", issn = "0892-6638", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565578000, title = "Kinetic Mechanism of Human Histidine Triad Nucleotide Binding Protein 1", journal = "Biochemistry", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565578000", id = "record", issn = "0006-2960", doi = "10.1021/bi301616c", volume = "52", pmcid = "PMC3835729" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140325-082556135, title = "Development of functional assays for p97/VCP inhibition", journal = "Cancer Research", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140325-082556135", id = "record", issn = "0008-5472", doi = "10.1158/1538-7445.AM2013-2146", volume = "73" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130301-075535357, title = "Structure–Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase", journal = "ChemMedChem", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130301-075535357", id = "record", issn = "1860-7179", doi = "10.1002/cmdc.201200520", volume = "8", pmcid = "PMC3662613" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110930-072701050, title = "Development of p97 AAA ATPase inhibitors", journal = "Autophagy", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110930-072701050", id = "record", issn = "1554-8627", doi = "10.4161/auto.7.9.16489", volume = "7", pmcid = "PMC3210319" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565437000, title = "E. coli Histidine Triad Nucleotide Binding Protein 1 (ecHinT) Is a Catalytic Regulator of D-Alanine Dehydrogenase (DadA) Activity In Vivo", journal = "PLoS ONE", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565437000", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0020897", volume = "6", pmcid = "PMC3130732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110606-105141967, title = "Quantitative Cell-based Protein Degradation Assays to Identify and Classify Drugs That Target the Ubiquitin-Proteasome System", journal = "Journal of Biological Chemistry", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110606-105141967", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M110.215319", volume = "286", pmcid = "PMC3089497" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565704000, title = "Role of Cathepsin A and Lysosomes in the Intracellular Activation of Novel Antipapillomavirus Agent GS-9191", journal = "Antimicrobial Agents and Chemotherapy", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565704000", id = "record", issn = "0066-4804", doi = "10.1128/aac.01603-10", volume = "55", pmcid = "PMC3088193" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110414-085357247, title = "Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110414-085357247", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1015312108", volume = "108", pmcid = "PMC3064330" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565930000, title = "Probing the Impact of the echinT C-Terminal Domain on Structure and Catalysis", journal = "Journal of Molecular Biology", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565930000", id = "record", issn = "0022-2836", doi = "10.1016/j.jmb.2010.09.066", volume = "404" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565985000, title = "Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection", journal = "Bioorganic and Medicinal Chemistry Letters", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565985000", id = "record", issn = "0960-894X", doi = "10.1016/j.bmcl.2009.09.067", volume = "19" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565456000, title = "Enzyme Nanorings", journal = "ACS Nano", year = "2008", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565456000", id = "record", issn = "1936-0851", doi = "10.1021/nn800577h", volume = "2", pmcid = "PMC2682639" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565905000, title = "Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein", journal = "Protein Expression and Purification", year = "2008", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565905000", id = "record", issn = "1046-5928", doi = "10.1016/j.pep.2008.03.024", volume = "60", pmcid = "PMC2617730" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565562000, title = "Impact of the C-Terminal Loop of Histidine Triad Nucleotide Binding Protein1 (Hint1) on Substrate Specificity", journal = "Biochemistry", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565562000", id = "record", issn = "0006-2960", doi = "10.1021/bi701244h", volume = "46" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565944000, title = "Evidence that Human Histidine Triad Nucleotide Binding Protein 3 (Hint3) is a Distinct Branch of the Histidine Triad (HIT) Superfamily", journal = "Journal of Molecular Biology", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565944000", id = "record", issn = "0022-2836", doi = "10.1016/j.jmb.2007.08.023", volume = "373" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565961000, title = "Engineered Monomeric Human Histidine Triad Nucleotide-binding Protein 1 Hydrolyzes Fluorogenic Acyl-adenylate and Lysyl-tRNA Synthetase-generated Lysyl-adenylate", journal = "Journal of Biological Chemistry", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565961000", id = "record", issn = "0021-9258", doi = "10.1074/jbc.m606972200", volume = "282" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565477000, title = "Phosphoramidate Pronucleotides:  A Comparison of the Phosphoramidase Substrate Specificity of Human and Escherichia coli Histidine Triad Nucleotide Binding Proteins", journal = "Molecular Pharmaceutics", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565477000", id = "record", issn = "1543-8384", doi = "10.1021/mp060070y", volume = "4" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565970000, title = "Lysyl-tRNA Synthetase-generated Lysyl-Adenylate Is a Substrate for Histidine Triad Nucleotide Binding Proteins", journal = "Journal of Biological Chemistry", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565970000", id = "record", issn = "0021-9258", doi = "10.1074/jbc.m610530200", volume = "282" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565490000, title = "Chemically Controlled Self-Assembly of Protein Nanorings", journal = "Journal of the American Chemical Society", year = "2006", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565490000", id = "record", issn = "0002-7863", doi = "10.1021/ja060631e", volume = "128" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220323-565463000, title = "Direct Measurement of Nucleoside Monophosphate Delivery from a Phosphoramidate Pronucleotide by Stable Isotope Labeling and LC−ESI⁻-MS/MS", journal = "Molecular Pharmaceutics", year = "2004", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565463000", id = "record", issn = "1543-8384", doi = "10.1021/mp0340338", volume = "1" }