Clemons, William
- Orta, Anna K. and Riera, Nadia, et el. (2023) The mechanism of the phage-encoded protein antibiotic from ΦX174; Science; Vol. 381; No. 6654; Art. No. eadg9091; 10.1126/science.adg9091
- Mays, Alfred and Byars-Winston, Angela, et el. (2023) Juneteenth in STEMM and the barriers to equitable science; Cell; Vol. 186; No. 12; 2510-2517; 10.1016/j.cell.2023.05.016
- Robertson, Gail A. and Clemons, William M., Jr., et el. (2023) Being Black in biophysics; Biophysical Journal; Vol. 122; No. 8; E1-E3; PMCID PMC10147933; 10.1016/j.bpj.2023.03.025
- Mitachi, Katsuhiko and Mingle, David, et el. (2022) Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor; Angewandte Chemie International Edition; Vol. 61; No. 31; e202203225; PMCID PMC9329268; 10.1002/anie.202203225
- Fry, Michelle Y. and Najdrova, Vladimira, et el. (2022) Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3; Nature Structural & Molecular Biology; Vol. 29; No. 8; 820-830; 10.1038/s41594-022-00798-4
- Fry, Michelle and Najdrova, Vladimira, et el. (2021) Structural characterization of the catalytic cycle of the chaperone Get3 from a human pathogen; Protein Science; Vol. 30; No. S1; 86; 10.1002/pro.4191
- Fry, Michelle Y. and Saladi, Shyam M., et el. (2021) Sequence-based features that are determinant for tail-anchored membrane protein sorting in eukaryotes; Traffic; Vol. 22; No. 9; 306-318; PMCID PMC8380732; 10.1111/tra.12809
- Fry, Michelle Y. and Saladi, Shyam M., et el. (2021) The STI1-domain is a flexible alpha‐helical fold with a hydrophobic groove; Protein Science; Vol. 30; No. 4; 882-898; 10.1002/pro.4049
- Lin, Ku-Feng and Fry, Michelle Y., et el. (2021) Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2; Journal of Biological Chemistry; Vol. 296; Art. No. 100441; 10.1016/j.jbc.2021.100441
- Mitachi, Katsuhiko and Kansal, Rita G., et el. (2020) DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors; Journal of Medicinal Chemistry; Vol. 63; No. 19; 10855-10878; PMCID PMC7554145; 10.1021/acs.jmedchem.0c00545
- Mitachi, Katsuhiko and Yun, Hyun Gi, et el. (2020) Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-based Assays; ACS Infectious Diseases; Vol. 6; No. 6; 1501-1516; PMCID PMC7286788; 10.1021/acsinfecdis.9b00242
- Mitachi, Katsuhiko and Kurosu, Shou M., et el. (2019) A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies; MethodsX; Vol. 6; 2305-2321; PMCID PMC6812346; 10.1016/j.mex.2019.09.031
- Mitachi, Katsuhiko and Kurosu, Shou M., et el. (2019) Semisynthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate; Organic Letters; Vol. 21; No. 4; 876-879; PMCID PMC6447083; 10.1021/acs.orglett.8b03716
- Saladi, Shyam M. and Javed, Nauman, et el. (2018) A statistical model for improved membrane protein expression using sequence-derived features; Journal of Biological Chemistry; Vol. 293; No. 13; 4913-4927; PMCID PMC5880134; 10.1074/jbc.RA117.001052
- Mitachi, Katsuhiko and Yun, Hyun Gi, et el. (2018) Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores; ACS Omega; Vol. 3; No. 2; 1726-1739; PMCID PMC5830699; 10.1021/acsomega.7b01740
- Fry, Michelle Y. and Clemons, William M., Jr. (2018) Complexity in targeting membrane proteins; Science; Vol. 359; No. 6374; 390-391; 10.1126/science.aar5992
- Niesen, Michiel J. M. and Marshall, Stephen S., et el. (2017) Improving membrane protein expression by optimizing integration efficiency; Journal of Biological Chemistry; Vol. 292; No. 47; 19537-19545; PMCID PMC5702688; 10.1074/jbc.M117.813469
- Mock, Jee-Young and Xu, Yue, et el. (2017) Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35; Proceedings of the National Academy of Sciences of the United States of America; Vol. 114; No. 44; 11679-11684; PMCID PMC5676875; 10.1073/pnas.1702940114
- Chu, Alexander E. and Saladi, Shyam M., et el. (2017) Towards a Universal Characterization of the Membrane Protein Expression Landscape; Biophysical Journal; Vol. 112; No. 3, Supp. 1; 188a; 10.1016/j.bpj.2016.11.1046
- Saladi, Shyam and Chu, Alexander E., et el. (2017) Statistical Models Robustly Predict Membrane Protein Expression in E. Coli; Biophysical Journal; Vol. 112; No. 3; 356a; 10.1016/j.bpj.2016.11.1929
- Schulte, Samuel J. and Saladi, Shyam, et el. (2017) Predicting Membrane Protein Expression in Yeast from Sequence-Derived Features; Biophysical Journal; Vol. 112; No. 3; 355a-356a; 10.1016/j.bpj.2016.11.1928
- Clemons, Bil (2017) Solving the Membrane Protein Expression Problem; Biophysical Journal; Vol. 112; No. 3; 329a-330a; 10.1016/j.bpj.2016.11.1783
- Yun, Hyun Gi and Jang, Kyoung-Soon, et el. (2016) The Structure of the UDP-Glc/GlcNAc 4-Epimerase from the Human Pathogen Campylobacter jejuni; Glycobiology; Vol. 26; No. 12; 1404; 10.1093/glycob/cww110
- Marshall, Stephen S. and Niesen, Michiel J. M., et el. (2016) A Link between Integral Membrane Protein Expression and Simulated Integration Efficiency; Cell Reports; Vol. 16; No. 8; 2169-2177; PMCID PMC5001948; 10.1016/j.celrep.2016.07.042
- Saladi, Shyam M. and Javed, Nauman, et el. (2016) A Machine Learning Approach to Heterologous Membrane Protein Overexpression; Biophysical Journal; Vol. 110; No. 3; 39A; 10.1016/j.bpj.2015.11.278
- Lin, Ku-Feng and Clemons, William M. (2016) Promiscuous Binding of Membrane Proteins on Flexible Co-Chaperones, Yeast Sgt2 and Human SGTA; Biophysical Journal; Vol. 110; No. 3; 560A; 10.1016/j.bpj.2015.11.2994
- Gristick, Harry B. and Rome, Michael E., et el. (2015) Mechanism of assembly of a substrate-transfer complex during tail-anchored protein targeting; Journal of Biological Chemistry; Vol. 290; No. 50; 30006-30017; PMCID PMC4705998; 10.1074/jbc.M115.677328
- Jang, Kyoung-Soon and Nani, Roger R., et el. (2015) A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides; Analytical and Bioanalytical Chemistry; Vol. 407; No. 20; 6181-6190; PMCID PMC4539134; 10.1007/s00216-015-8798-8
- Mock, Jee-Young and Clemons, William M., Jr. (2015) Capturing the signal; eLife; Vol. 2015; No. 4; Art. No. e09315; PMCID PMC4497382; 10.7554/eLife.09315
- Mitachi, Katsuhiko and Siricilla, Shajila, et el. (2015) Chemoenzymatic syntheses of water-soluble lipid I fluorescent probes; Tetrahedron Letters; Vol. 56; No. 23; 3441-3446; PMCID PMC4505380; 10.1016/j.tetlet.2015.01.044
- Mock, Jee-Young and Chartron, Justin William, et el. (2015) Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain; Proceedings of the National Academy of Sciences of the United States of America; Vol. 112; No. 1; 106-111; PMCID PMC4291651; 10.1073/pnas.1402745112
- Müller, Axel and Beeby, Morgan, et el. (2014) Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni; MicrobiologyOpen; Vol. 3; No. 5; 702-710; PMCID PMC4234261; 10.1002/mbo3.200
- Gristick, Harry B. and Rao, Meera, et el. (2014) Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4; Nature Structural & Molecular Biology; Vol. 21; No. 5; 437-442; PMCID PMC4386898; 10.1038/nsmb.2813
- Gristick, Harry and Rao, Meera, et el. (2014) The structure of a tail-anchor membrane protein-binding complex reveals the regulation of Get3 by Get4; FASEB Journal; Vol. 28; No. 1; Art. No. 950.4
- Jang, Kyoung-Soon and Sweredoski, Michael J., et el. (2014) Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni; Journal of Proteomics; Vol. 98; 90-98; PMCID PMC4534003; 10.1016/j.jprot.2013.12.014
- Liu, Yanfen and Soetandyo, Nia, et el. (2014) USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation; eLife; Vol. 2014; No. 3; Art. No. e01369; PMCID PMC3889402; 10.7554/eLife.01369
- Ramasamy, Sureshkumar and Abrol, Ravinder, et el. (2013) The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation; Structure; Vol. 21; No. 5; 777-788; PMCID PMC3653977; 10.1016/j.str.2013.03.004
- Rome, Michael E. and Rao, Meera, et el. (2013) Precise timing of ATPase activation drives targeting of tail-anchored proteins; Proceedings of the National Academy of Sciences of the United States of America; Vol. 110; No. 19; 7666-7671; PMCID PMC3651441; 10.1073/pnas.1222054110
- Rao, Meera and Rome, Michael E., et el. (2013) Precise Timing of ATPase Activation Drives Targeting of Tail-Anchored Proteins; Biophysical Journal; Vol. 104; No. 2; 572A; 10.1016/j.bpj.2012.11.3178
- Chartron, Justin W. and VanderVelde, David G., et el. (2012) Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface; Cell Reports; Vol. 2; No. 6; 1620-1632; PMCID PMC3654831; 10.1016/j.celrep.2012.10.010
- Tanaka, Shiho and Clemons, William M., Jr. (2012) Minimal requirements for inhibition of MraY by lysis protein E
from bacteriophage ΦX174; Molecular Microbiology; Vol. 85; No. 5; 975-985; PMCID PMC3429702; 10.1111/j.1365-2958.2012.08153.x
- Clemons, Bil and Chartron, Justin, et el. (2012) Higher order assemblies in the GET membrane protein-targeting pathway; Protein Science; Vol. 21; No. S1; 65
- Mock, Jeeyoung and Chartron, Justin, et el. (2012) The Structural and Biochemical Characterization of Members of the Mammalian TA Protein Sorting Complex; Protein Science; Vol. 21; No. S1; 230; 10.1002/pro.2113
- Chartron, Justin William and Clemons, William M., Jr. (2012) Structural investigations of the Get4/Get5/Sgt2 complex; FASEB Journal; Vol. 26; Art. No. 749.4
- Clemons, William and Chartron, Justin, et el. (2012) Higher order assemblies in the GET membrane protein targeting pathway; FASEB Journal; Vol. 26; Art. No. 229.2
- Chartron, Justin W. and Clemons, William M., Jr., et el. (2012) The complex process of GETting tail-anchored membrane proteins to the ER; Current Opinion in Structural Biology; Vol. 22; No. 2; 217-224; PMCID PMC3359790; 10.1016/j.sbi.2012.03.001
- Chartron, Justin W. and VanderVelde, David G., et el. (2012) Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex; Journal of Biological Chemistry; Vol. 287; No. 11; 8310-8317; PMCID PMC3318709; 10.1074/jbc.M111.333252
- Suloway, Christian J. M. and Rome, Michael E., et el. (2012) Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue; EMBO Journal; Vol. 31; No. 3; 707-719; PMCID PMC3273380; 10.1038/emboj.2011.433
- Chartron, Justin W. and Gonzalez, Grecia M., et el. (2011) A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 Complex; Journal of Biological Chemistry; Vol. 286; No. 39; 34325-34334; PMCID PMC3190793; 10.1074/jbc.M111.277798
- Chartron, Justin W. and Suloway, Christian J. M., et el. (2010) Structural characterization of the Get4/Get5 complex and its interaction with Get3; Proceedings of the National Academy of Sciences of the United States of America; Vol. 107; No. 27; 12127-12132; PMCID PMC2901463; 10.1073/pnas.1006036107
- Suloway, Christian J. M. and Chartron, Justin W., et el. (2009) Model for eukaryotic tail-anchored protein binding based on the structure of Get3; Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 35; 14849-14854; PMCID PMC2736419; 10.1073/pnas.0907522106
- Ramasamy, Suresh Kumar and Clemons, William M. (2009) Structure of the twin-arginine signal-binding protein DmsD from Escherichia coli; Acta Crystallographica. Section F, Structural Biology and Crystallization Communications; Vol. 65; No. 8; 746-750; PMCID PMC2720324; 10.1107/S1744309109023811
- Ménétret, Jean-François and Schaletzky, Julia, et el. (2007) Ribosome Binding of a Single Copy of the SecY Complex: Implications for Protein Translocation; Molecular Cell; Vol. 28; No. 6; 1083-1092; 10.1016/j.molcel.2007.10.034
- Smith, Margaret A. and Clemons, William M., Jr., et el. (2005) Modeling the Effects of prl Mutations on the Escherichia coli SecY Complex; Journal of Bacteriology; Vol. 187; No. 18; 6454-6465; PMCID PMC1236629; 10.1128/JB.187.18.6454-6465.2005
- Cannon, Kurt S. and Or, Eran, et el. (2005) Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY; Journal of Cell Biology; Vol. 169; No. 2; 219-225; PMCID PMC2171872; 10.1083/jcb.200412019
- Clemons, William M., Jr. and Ménétret, Jean-François, et el. (2004) Structural insight into the protein translocation channel; Current Opinion in Structural Biology; Vol. 14; No. 4; 390-396; 10.1016/j.sbi.2004.07.006
- Osborne, Andrew R. and Clemons, William M., Jr., et el. (2004) A large conformational change of the translocation ATPase SecA; Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 30; 10937-10942; PMCID PMC491988; 10.1073/pnas.0401742101
- van den Berg, Bert and Black, Paul N., et el. (2004) Crystal Structure of the Long-Chain Fatty Acid Transporter FadL; Science; Vol. 304; No. 5676; 1506-1509; 10.1126/science.1097524
- van den Berg, Bert and Clemons, William M., Jr., et el. (2004) X-ray structure of a protein-conducting channel; Nature; Vol. 427; No. 6969; 36-44; 10.1038/nature02218
- Brodersen, D. E. and Clemons, W. M., Jr., et el. (2003) Phasing the 30S ribosomal subunit structure; Acta Crystallographica Section D: Biological Crystallography; Vol. 59; No. 11; 2044-2050; 10.1107/s0907444903017669
- Brodersen, Ditlev E. and Clemons, William M., Jr., et el. (2002) Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA; Journal of Molecular Biology; Vol. 316; No. 3; 725-768; 10.1006/jmbi.2001.5359
- Clemons, William M., Jr. and Brodersen, Ditlev E., et el. (2001) Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination; Journal of Molecular Biology; Vol. 310; No. 4; 827-843; 10.1006/jmbi.2001.4778
- Ogle, James M. and Brodersen, Ditlev E., et el. (2001) Recognition of Cognate Transfer RNA by the 30S Ribosomal Subunit; Science; Vol. 292; No. 5518; 897-902; 10.1126/science.1060612
- Carter, Andrew P. and Clemons, William M., Jr., et el. (2001) Crystal Structure of an Initiation Factor Bound to the 30S Ribosomal Subunit; Science; Vol. 291; No. 5503; 498-501; 10.1126/science.1057766
- Brodersen, D. E. and Carter, A. P., et el. (2001) Atomic Structures of the 30S Subunit and Its Complexes with Ligands and Antibiotics; Cold Spring Harbor Symposia on Quantitative Biology; Vol. 66; 17-32; 10.1101/sqb.2001.66.17
- Brodersen, Ditlev E. and Clemons, William M., Jr., et el. (2000) Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit; Cell; Vol. 103; No. 7; 1143-1154; 10.1016/s0092-8674(00)00216-6
- Carter, Andrew P. and Clemons, William M., et el. (2000) Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics; Nature; Vol. 407; No. 6802; 340-348; 10.1038/35030019
- Wimberly, Brian T. and Brodersen, Ditlev E., et el. (2000) Structure of the 30S ribosomal subunit; Nature; Vol. 407; No. 6802; 327-339; 10.1038/35030006
- Allard, Peter and Rak, Alexey V., et el. (2000) Another piece of the ribosome: solution structure of S16 and its location in the 30S subunit; Structure; Vol. 8; No. 8; 875-882; 10.1016/s0969-2126(00)00177-5
- Clemons, William M., Jr. and Gowda, Krishne, et el. (1999) Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding; Journal of Molecular Biology; Vol. 292; No. 3; 697-705; 10.1006/jmbi.1999.3090
- Clemons, William M., Jr. and May, Joanna L. C., et el. (1999) Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution; Nature; Vol. 400; No. 6747; 833-840; 10.1038/23631
- Gowda, Krishne and Clemons, William M., Jr., et el. (1999) Expression, purification, and crystallography of the conserved methionine-rich domain of human signal recognition particle 54 kda protein; Protein Science; Vol. 8; No. 5; 1144-1151; PMCID PMC2144335; 10.1110/ps.8.5.1144
- McCutcheon, John P. and Agrawal, Rajendra K., et el. (1999) Location of translational initiation factor IF3 on the small ribosomal subunit; Proceedings of the National Academy of Sciences of the United States of America; Vol. 96; No. 8; 4301-4306; PMCID PMC16327; 10.1073/pnas.96.8.4301
- Clemons, William M., Jr. and Davies, Christopher, et el. (1998) Conformational variability of the N-terminal helix in the structure of ribosomal protein S15; Structure; Vol. 6; No. 4; 429-438; 10.1016/s0969-2126(98)00045-8