Expression of mRNA Encoding Rat Brain Ca²⁺ Channels in Xenopus Oocytes

Year: 1988

DOI: 10.1007/978-3-642-73914-9_22

Our laboratory is seeking a mechanistic picture of the action of the voltage-dependent, Ca²⁺-selective ion channels that partially underlie the electrical excitability of membranes. Full explanations will ultimately require pictures of such molecules at atomic resolution (as obtained with X-ray crystallography) in all their states (closed, open, inactivated, etc.). Such structural information is not yet available for any channel.