Dervan, Peter
Dervan, Peter B. (2022) Skydiving into the interface of chemistry and biology ; Chemical & Engineering News; Vol. 100; No. 10; 36-40
Oh, Juntaek and Jia, Tiezheng, et el. (2022) RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 119; No. 3; Art. No. e2114065119; PMCID PMC8784135; 10.1073/pnas.2114065119
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Chen, Chien-yu and Li, Yang, et el. (2020) Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides ; Medicinal Chemistry Research; Vol. 29; No. 4; 607-616; PMCID PMC8455084; 10.1007/s00044-019-02493-4
Kurmis, Alexis A. and Dervan, Peter B. (2019) Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide ; Nucleic Acids Research; Vol. 47; No. 8; 3828-3835; PMCID PMC6486638; 10.1093/nar/gkz153
Dervan, Peter B. (2019) A Personal Perspective on Chemical Biology: Before the Beginning ; Israel Journal of Chemistry; Vol. 59; No. 1-2; 71-83; 10.1002/ijch.201800171
Dervan, Peter B. (2019) Ronald Breslow Award for Achievement in Biomimetic Chemistry: David A. Tirrell ; Chemical and Engineering News; Vol. 97; No. 3; 51
Diaz-Perez, S. and Kane, N., et el. (2018) Radiosensitization by a Pyrrole-Imidazole Polyamide Through Interference with DNA Repair ; International Journal of Radiation Oncology Biology Physics; Vol. 102; No. 3, Supp.; e155; 10.1016/j.ijrobp.2018.07.604
Houk, K. N. and Caserio, Marjorie C., et el. (2018) J. D. Roberts Special Issue ; Journal of Physical Organic Chemistry; Vol. 31; No. 8; Art. No. e3886; 10.1002/poc.3886
Diaz-Perez, Silvia and Kane, Nathanael, et el. (2018) Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide ; PLoS ONE; Vol. 13; No. 5; Art. No. e0196803; PMCID PMC5929528; 10.1371/journal.pone.0196803
Dervan, Peter B. (2018) Herbert C. Brown Award for Creative Research in Synthetic Methods: Gregory C. Fu ; Chemical and Engineering News; Vol. 96; No. 2; 40
Xu, Jun and Lahiri, Indrajit, et el. (2017) Structural basis for the initiation of eukaryotic transcription-coupled DNA repair ; Nature; Vol. 551; No. 7682; 653-657; PMCID PMC5907806; 10.1038/nature24658
Kurmis, Alexis A. and Yang, Fei, et el. (2017) A pyrrole-imidazole polyamide is active against enzalutamide-resistant prostate cancer ; Cancer Research; Vol. 77; No. 9; 2207-2212; 10.1158/0008-5472.CAN-16-2503
Xu, Liang and Wang, Wei, et el. (2016) RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 113; No. 44; 12426-12431; PMCID PMC5098678; 10.1073/pnas.1612745113
Dervan, Peter B. (2016) Ahmed H. Zewail (1946-2016) ; Science; Vol. 353; No. 6304; 1103-1103; 10.1126/science.aai8466
Gerhardt, Jeannine and Bhalla, Angela D., et el. (2016) Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells ; Cell Reports; Vol. 16; No. 5; 1218-1227; PMCID PMC5028224; 10.1016/j.celrep.2016.06.075
Szablowski, Jerzy O. and Raskatov, Jevgenij A., et el. (2016) An HRE-binding Py-Im polyamide impairs hypoxic signaling in tumors ; Molecular Cancer Therapeutics; Vol. 15; No. 4; 608-617; PMCID PMC4873353; 10.1158/1535-7163.MCT-15-0719
Mysore, Veena S. and Szablowski, Jerzy, et el. (2016) A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma has Potent Anti-tumor Activity ; Molecular Cancer Research; Vol. 14; No. 3; 253-266; PMCID PMC4794370; 10.1158/1541-7786.MCR-15-0361
Hargrove, Amanda E. and Martínez, Thomas F., et el. (2015) Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide ; PLoS ONE; Vol. 10; No. 11; Art. No. e0143161; PMCID PMC4646452; 10.1371/journal.pone.0143161
Kummer, N. T. and Yang, F., et el. (2015) Radiosensitization by DNA, Binding Pyrrole, Imidazole Polyamides ; International Journal of Radiation Oncology Biology Physics; Vol. 93; No. 3, Supp. 1; E537-E538; 10.1016/j.ijrobp.2015.07.1923
Kang, JeenJoo S. and Dervan, Peter B. (2015) A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma ; Quarterly Reviews of Biophysics; Vol. 48; No. 4; 453-464; PMCID PMC4743504; 10.1017/S0033583515000104
Kummer, N. T. and Yang, F., et el. (2015) DNA Repair Interference with Sequence Specific DNA Binding Pyrrole Imidazole Polyamides; a Novel Radiation Sensitizer ; Strahlentherapie und Onkologie; Vol. 191; No. 11; 902-903; 10.1007/s00066-015-0903-6
Raskatov, Jevgenij A. and Szablowski, Jerzy O., et el. (2014) Tumor Xenograft Uptake of a Pyrrole−Imidazole (Py-Im) Polyamide Varies as a Function of Cell Line Grafted ; Journal of Medicinal Chemistry; Vol. 57; No. 20; 8471-8476; PMCID PMC4207538; 10.1021/jm500964c
Martínez, Thomas F. and Philips, John W., et el. (2014) Replication stress by Py–Im polyamides induces a non-canonical ATR-dependent checkpoint response ; Nucleic Acids Research; Vol. 42; No. 18; 11546-11559; PMCID PMC4191428; 10.1093/nar/gku866
Mysore, Veena S. and Nickols, Nicholas G., et el. (2014) Targeting hypoxia-mediated gene transcription with a novel polyamide drug designed to disrupt the HIF1α/β heterodimer binding overcomes resistance to hypoxia in myeloma cell lines ; Cancer Research; Vol. 74; No. 19 Suppleme; Art. No. 5132; 10.1158/1538-7445.AM2014-5132
Raskatov, Jevgenij A. and Puckett, James W., et el. (2014) A C-14 labeled Py–Im polyamide localizes to a subcutaneous prostate cancer tumor ; Bioorganic and Medicinal Chemistry; Vol. 22; No. 16; 4371-4375; PMCID PMC4134956; 10.1016/j.bmc.2014.04.010
Kang, JeenJoo S. and Meier, Jordan L., et el. (2014) Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition ; Journal of the American Chemical Society; Vol. 136; No. 9; 3687-3694; PMCID PMC3985849; 10.1021/ja500211z
Nickols, N. and Yang, F., et el. (2013) Radiosensitization by High Affinity Programmable Minor Groove
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Yang, Fei and Nickols, Nicholas G., et el. (2013) Animal Toxicity of Hairpin Pyrrole-Imidazole Polyamides Varies with the Turn Unit ; Journal of Medicinal Chemistry; Vol. 56; No. 18; 7449-7457; PMCID PMC3788622; 10.1021/jm401100s
Nickols, Nicholas G. and Szablowski, Jerzy O., et el. (2013) Activity of a Py–Im Polyamide Targeted to the Estrogen Response Element ; Molecular Cancer Therapeutics; Vol. 12; No. 5; 675-684; PMCID PMC3651785; 10.1158/1535-7163.MCT-12-1040
Nickols, Nicholas G. and Yang, Fei, et el. (2013) Antitumor activity of a pyrrole-imidazole polyamide in three tumor xenograft models ; Cancer Research; Vol. 73; No. 8; Art. No. 1130; 10.1158/1538-7445.AM2013-1130
Edwards, Jonathan S. and Betts, Laurie, et el. (2013) Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 110; No. 8; 2804-2809; PMCID PMC3581901; 10.1073/pnas.1219701110
Yang, Fei and Nickols, Nicholas G., et el. (2013) Antitumor activity of a pyrrole-imidazole polyamide ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 110; No. 5; 1863-1868; PMCID PMC3562772; 10.1073/pnas.1222035110
Li, Benjamin C. and Montgomery, David C., et el. (2013) Synthesis of Cyclic Py-Im Polyamide Libraries ; Journal of Organic Chemistry; Vol. 78; No. 1; 124-133; PMCID PMC3538502; 10.1021/jo302053v
Chenoweth, David M. and Meier, Jordan L., et el. (2013) Pyrrole-Imidazole Polyamides Distinguish Between Double-Helical DNA and RNA ; Angewandte Chemie International Edition; Vol. 52; No. 1; 415-418; PMCID PMC3535541; 10.1002/anie.201205775
Meier, Jordan L. and Yu, Abigail S., et el. (2012) Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing ; Journal of the American Chemical Society; Vol. 134; No. 42; 17814-17822; PMCID PMC3483022; 10.1021/ja308888c
Raskatov, Jevgenij A. and Nickols, Nicholas G., et el. (2012) Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 109; No. 40; 16041-16045; PMCID PMC3479560; 10.1073/pnas.1214267109
Synold, Timothy W. and Xi, Bixin, et el. (2012) Single-dose pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in mice ; Cancer Chemotherapy and Pharmacology; Vol. 70; No. 4; 617-625; PMCID PMC3456924; 10.1007/s00280-012-1954-3
Du, Jintang and Campau, Erica, et el. (2012) Role of Mismatch Repair Enzymes in GAA•TTC Triplet-repeat Expansion in Friedreich Ataxia Induced Pluripotent Stem Cells ; Journal of Biological Chemistry; Vol. 287; No. 35; 29861-29872; PMCID PMC3436184; 10.1074/jbc.M112.391961
Jespersen, Christine and Soragni, Elisabetta, et el. (2012) Chromatin structure determines accessibility of a hairpin polyamide–chlorambucil conjugate at histone H4 genes in pancreatic cancer cells ; Bioorganic and Medicinal Chemistry Letters; Vol. 22; No. 12; 4068-4071; PMCID PMC3362666; 10.1016/j.bmcl.2012.04.090
Hargrove, Amanda E. and Raskatov, Jevgenij A., et el. (2012) Characterization and Solubilization of Pyrrole−Imidazole Polyamide Aggregates ; Journal of Medicinal Chemistry; Vol. 55; No. 11; 5425-5432; PMCID PMC3375050; 10.1021/jm300380a
Puckett, James W. and Green, Joshua T., et el. (2012) Microwave Assisted Synthesis of Py-Im Polyamides ; Organic Letters; Vol. 14; No. 11; 2774-2777; PMCID PMC3365540; 10.1021/ol3010003
Raskatov, Jevgenij A. and Hargrove, Amanda E., et el. (2012) Pharmacokinetics of Py-Im Polyamides Depend on Architecture:
Cyclic versus Linear ; Journal of the American Chemical Society; Vol. 134; No. 18; 7995-7999; PMCID PMC3349014; 10.1021/ja302588v
Meier, Jordan L. and Montgomery, David C., et el. (2012) Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns ; Nucleic Acids Research; Vol. 40; No. 5; 2345-2356; PMCID PMC3300022; 10.1093/nar/gkr970
Raskatov, Jevgenij A. and Meier, Jordan L., et el. (2012) Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 109; No. 4; 1023-1028; PMCID PMC3268328; 10.1073/pnas.1118506109
Zhang, Yi and Sicot, Géraldine, et el. (2011) Targeting a DNA Binding Motif of the EVI1 Protein by a Pyrrole−Imidazole Polyamide ; Biochemistry; Vol. 50; No. 48; 10431-10441; PMCID PMC3619939; 10.1021/bi200962u
Muzikar, Katy A. and Meier, Jordan L., et el. (2011) Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA ; Organic Letters; Vol. 13; No. 20; 5612-5615; PMCID PMC3195311; 10.1021/ol202285y
Chenoweth, David M. and Dervan, Peter B. (2010) Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding ; Journal of the American Chemical Society; Vol. 132; No. 41; 14521-14529; PMCID PMC2954530; 10.1021/ja105068b
Jacobs, Claire S. and Dervan, Peter B. (2009) Modifications at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in Cell Culture ; Journal of Medicinal Chemistry; Vol. 52; No. 23; 7380-7388; PMCID PMC2788682; 10.1021/jm900256f
Muzikar, Katy A. and Nickols, Nicholas G., et el. (2009) Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 39; 16598-16603; PMCID PMC2744631; 10.1073/pnas.0909192106
Chenoweth, David M. and Harki, Daniel A., et el. (2009) Oligomerization Route to Py-Im Polyamide Macrocycles ; Organic Letters; Vol. 11; No. 16; 3590-3593; PMCID PMC2736337; 10.1021/ol901311m
Chenoweth, David M. and Dervan, Peter B. (2009) Allosteric modulation of DNA by small molecules ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 32; 13175-13179; PMCID PMC2726366; 10.1073/pnas.0906532106
Farkas, Michelle E. and Li, Benjamin C., et el. (2009) DNA sequence selectivity of hairpin polyamide turn units ; Bioorganic and Medicinal Chemistry Letters; Vol. 19; No. 14; 3919-3923; PMCID PMC3062503; 10.1016/j.bmcl.2009.03.072
Ho, Dominik and Dose, Christian, et el. (2009) Quantitative detection of small molecule/DNA complexes employing a force-based and label-free DNA-microarray ; Biophysical Journal; Vol. 96; No. 11; 4661-4671; PMCID PMC2711479; 10.1016/j.bpj.2009.02.059
Chenoweth, David M. and Harki, Daniel A., et el. (2009) Solution-phase synthesis of pyrrole-imidazole polyamides ; Journal of the American Chemical Society; Vol. 131; No. 20; 7175-7181; PMCID PMC2689157; 10.1021/ja901307m
Chenoweth, David M. and Harki, Daniel A., et el. (2009) Cyclic pyrrole-imidazole polyamides targeted to the androgen response element ; Journal of the American Chemical Society; Vol. 131; No. 20; 7182-7188; PMCID PMC2689155; 10.1021/ja901309z
Sicot, Géraldine and Vogel, Marion, et el. (2008) Development of a novel polyamide-based agent to inhibit EVI1 function ; Blood; Vol. 112; No. 11; 920
Hsu, Carey F. and Dervan, Peter B. (2008) Quantitating the concentration of Py-Im polyamide–fluorescein conjugates in live cells ; Bioorganic and Medicinal Chemistry Letters; Vol. 18; No. 22; 5851-5855; PMCID PMC2587135; 10.1016/j.bmcl.2008.05.063
Hsu, Carey F. and Dervan, Peter B. (2008) Quantitating the Concentration of Polyamide-Fluorescein Conjugates in Live Cells ; Bioorganic Medicinal Chemistry Letters Online; Vol. 18; No. 22; 5851-5; 10.1016/j.bmcl.2008.05.063
Harki, Daniel A. and Satyamurthy, Nagichettiar, et el. (2008) In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 105; No. 35; 13039-13044; PMCID PMC2529060; 10.1073/pnas.0806308105
Dose, Christian and Farkas, Michelle E., et el. (2008) Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit ; Journal of the American Chemical Society; Vol. 130; No. 21; 6859-6866; PMCID PMC3063708; 10.1021/ja800888d
Moretti, Rocco and Donato, Leslie J., et el. (2008) Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly ; ACS Chemical Biology; Vol. 3; No. 4; 220-229; PMCID PMC3060767; 10.1021/cb700258r
Chou, C. James and Farkas, Michelle E., et el. (2008) Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia ; Molecular Cancer Therapeutics; Vol. 7; No. 4; 769-778; PMCID PMC2376757; 10.1158/1535-7163.MCT-08-0130
Cohen, Justin D. and Sadowski, John P., et el. (2008) Programming multiple protein patterns on a single DNA nanostructure ; Journal of the American Chemical Society; Vol. 130; No. 2; 402-403; 10.1021/ja0772400
Farkas, Michelle E. and Tsai, Sherry M., et el. (2007) α-Diaminobutyric acid-linked hairpin polyamides ; Bioorganic and Medicinal Chemistry; Vol. 15; No. 22; 6927-6936; PMCID PMC2140246; 10.1016/j.bmc.2007.07.019
Stafford, Ryan L. and Dervan, Peter B. (2007) The reach of linear protein-DNA dimerizers ; Journal of the American Chemical Society; Vol. 129; No. 45; 14026-14033; PMCID PMC2547995; 10.1021/ja075247b
Dose, Christian and Ho, Dominik, et el. (2007) Recognition of "mirror-image" DNA by small molecules ; Angewandte Chemie International Edition; Vol. 46; No. 44; 8384-8387; 10.1002/anie.200703007
Cohen, Justin D. and Sadowski, John P., et el. (2007) Addressing single molecules on DNA nanostructures ; Angewandte Chemie International Edition; Vol. 46; No. 42; 7956-1959; 10.1002/anie.200702767
Puckett, James W. and Muzikar, Katy A., et el. (2007) Quantitative microarray profiling of DNA-binding molecules ; Journal of the American Chemical Society; Vol. 129; No. 40; 12310-12319; PMCID PMC3066056; 10.1021/ja0744899
Nickols, Nicholas G. and Jacobs, Claire S., et el. (2007) Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface ; ACS Chemical Biology; Vol. 2; No. 8; 561-571; PMCID PMC3060759; 10.1021/cb700110z
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Nickols, Nicholas G. and Dervan, Peter B. (2007) Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 104; No. 25; 10418-10423; PMCID PMC1965528; 10.1073/pnas.0704217104
Stafford, Ryan L. and Arndt, Hans-Dieter, et el. (2007) Minimization of a Protein−DNA Dimerizer ; Journal of the American Chemical Society; Vol. 129; No. 9; 2660-2668; PMCID PMC3064071; 10.1021/ja067971k
Chenoweth, David M. and Viger, Anne, et el. (2007) Fluorescent Sequence-Specific dsDNA Binding Oligomers ; Journal of the American Chemical Society; Vol. 129; No. 8; 2216-2217; PMCID PMC3066654; 10.1021/ja0682576
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Nickols, Nicholas G. and Jacobs, Claire S., et el. (2007) Improved nuclear localization of DNA-binding polyamides ; Nucleic Acids Research; Vol. 35; No. 2; 363-370; PMCID PMC1802595; 10.1093/nar/gkl1042
Tsai, Sherry M. and Farkas, Michelle E., et el. (2007) Unanticipated differences between α- and γ-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates ; Nucleic Acids Research; Vol. 35; No. 1; 307-316; PMCID PMC1802559; 10.1093/nar/gkl1025
Viger, Anne and Dervan, Peter B. (2006) Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site ; Bioorganic and Medicinal Chemistry; Vol. 14; No. 24; 8539-8549; 10.1016/j.bmc.2006.08.028
Burnett, Ryan and Melander, Christian, et el. (2006) DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA·TTC repeats in Friedreich's ataxia ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 103; No. 31; 11497-11502; PMCID PMC1544198; 10.1073/pnas.0604939103
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Alvarez, David and Chou, C. James, et el. (2006) A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate ; Cell Cycle; Vol. 5; No. 14; 1537-1548; 10.4161/cc.5.14.2913
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Fechter, Eric J. and Olenyuk, Bogdan, et el. (2005) Sequence-specific fluorescence detection of DNA by polyamide-thiazole orange conjugates ; Journal of the American Chemical Society; Vol. 127; No. 47; 16685-16691; 10.1021/ja054650k
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Gearhart, Micah D. and Dickinson, Liliane, et el. (2005) Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides ; Biochemistry; Vol. 44; No. 11; 4196-4203; 10.1021/bi047872o
Philips, Brian J. and Chang, Aileen Y., et el. (2005) DNA damage effects of a polyamide-CBI conjugate in SV40 virions ; Molecular Pharmacology; Vol. 67; No. 3; 877-882; 10.1124/mol.104.006254
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Dickinson, Liliane A. and Burnett, Ryan, et el. (2004) Arresting cancer proliferation by small-molecule gene regulation ; Chemistry and Biology; Vol. 11; No. 11; 1583-1594; 10.1016/j.chembiol.2004.09.004
Ylisastigui, Loyda and Coull, Jason J., et el. (2004) Polyamides Reveal a Role for Repression in Latency within Resting T Cells of HIV-Infected Donors ; Journal of Infectious Diseases; Vol. 190; No. 8; 1429-1437; 10.1086/423822
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Marques, Michael A. and Doss, Raymond M., et el. (2004) Expanding the repertoire of heterocycle ring pairs for programmable minor groove DNA recognition ; Journal of the American Chemical Society; Vol. 126; No. 33; 10339-10349; 10.1021/ja0486465
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Doss, Raymond M. and Marques, Michael A., et el. (2004) DNA minor-groove recognition by 3-methylthiophene/pyrrole pair ; Chemistry and Biodiversity; Vol. 1; No. 6; 886-899; 10.1002/cbdv.200490071
Edayathumangalam, Rajeswari S. and Weyermann, Philipp, et el. (2004) Molecular recognition of the nucleosomal "supergroove" ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 18; 6864-6869; PMCID PMC406433; 10.1073/pnas.0401743101
Edelson, Benjamin S. and Best, Timothy P., et el. (2004) Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates ; Nucleic Acids Research; Vol. 32; No. 9; 2802-2818; PMCID PMC419610; 10.1093/nar/gkh609
Nguyen-Hackley, Doan H. and Ramm, Elizabeth, et el. (2004) Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands ; Biochemistry; Vol. 43; No. 13; 3880-3890; 10.1021/bi030223c
Poulin-Kerstien, Adam T. and Dervan, Peter B. (2003) DNA-templated dimerization of hairpin polyamides ; Journal of the American Chemical Society; Vol. 125; No. 51; 15811-21; 10.1021/ja030494a
Arndt, Hans-Dieter and Hauschild, Karl E., et el. (2003) Toward artificial developmental regulators ; Journal of the American Chemical Society; Vol. 125; No. 44; 13322-13323; 10.1021/ja0371395
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Cho, Junhyeong and Parks, Michelle E., et el. (1995) Cyclic polyamides for recognition in the minor groove of DNA ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 92; No. 22; 10389-10392; PMCID PMC40802
Baliga, Ramesh and Singleton, Jennifer W., et el. (1995) RecA·Oligonucleotide Filaments Bind in the Minor Groove of Double-Stranded DNA ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 92; No. 22; 10393-10397; PMCID PMC40803
Chen, Lin and Oakley, Martha G., et el. (1995) Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp ; Current Biology; Vol. 5; No. 8; 882-889; 10.1016/S0960-9822(95)00178-3
Greenberg, William A. and Dervan, Peter B. (1995) Energetics of Formation of Sixteen Triple Helical Complexes Which Vary at a Single Position Within a Purine Motif ; Journal of the American Chemical Society; Vol. 117; No. 18; 5016-5022; 10.1021/ja00123a002
Colocci, Natalia and Dervan, Peter B. (1995) Cooperative Triple-Helix Formation at Adjacent DNA Sites: Sequence Composition Dependence at the Junction ; Journal of the American Chemical Society; Vol. 117; No. 17; 4781-4787; 10.1021/ja00122a007
Priestley, E. Scott and Dervan, Peter B. (1995) Sequence Composition Effects on the Energetics of Triple Helix Formation by Oligonucleotides Containing a Designed Mimic of Protonated Cytosine ; Journal of the American Chemical Society; Vol. 117; No. 17; 4761-4765; 10.1021/ja00122a004
Mrksich, Milan and Dervan, Peter B. (1995) Recognition in the Minor Groove of DNA at 5'-(A,T)GCGC(A,T)-3' by a Four Ring Tripeptide Dimer. Reversal of the Specificity of the Natural Product Distamycin ; Journal of the American Chemical Society; Vol. 117; No. 12; 3325-3332; 10.1021/ja00117a002
Hunziker, Jürg and Priestley, E. Scott, et el. (1995) Design of an N^7-Glycosylated Purine Nucleoside for Recognition of GC Base Pairs by Triple Helix Formation ; Journal of the American Chemical Society; Vol. 117; No. 9; 2661-2662; 10.1021/ja00114a036
Best, George C. and Dervan, Peter B. (1995) Energetics of Formation of Sixteen Triple Helical Complexes Which Vary at a Single Position within a Pyrimidine Motif ; Journal of the American Chemical Society; Vol. 117; No. 4; 1187-1193; 10.1021/ja00109a001
Singleton, Scott F. and Dervan, Peter B. (1994) Temperature Dependence of the Energetics of Oligonucleotide-Directed Triple-Helix Formation at a Single DNA Site ; Journal of the American Chemical Society; Vol. 116; No. 23; 10376-10382; 10.1021/ja00102a003
Geierstanger, Bernhard H. and Mrksich, Milan, et el. (1994) Design of a G•C-Specific DNA Minor Groove-Binding Peptide ; Science; Vol. 266; No. 5185; 646-650; 10.1126/science.7939719
Khundkar, Lutfur R. and Perry, Joseph W., et el. (1994) Weak Temperature Dependence of Electron Transfer Rates in Fixed-Distance Porphyrin-Quinone Model Systems ; Journal of the American Chemical Society; Vol. 116; No. 21; 9700-9709; 10.1021/ja00100a040
Mrksich, Milan and Parks, Michell E., et el. (1994) Hairpin Peptide Motif. A New Class of Oligopeptides for Sequence-Specific Recognition in the Minor Groove of Double-Helical DNA ; Journal of the American Chemical Society; Vol. 116; No. 18; 7983-7988; 10.1021/ja00097a004
Han, Hogyu and Schepartz, Alanna, et el. (1994) Mapping RNA Regions in Eukaryotic Ribosomes That Are Accessible to Methidiumpropyl-EDTA•Fe(II) and EDTA•Fe(II) ; Biochemistry; Vol. 33; No. 33; 9831-9844
Han, Hogyu and Dervan, Peter B. (1994) Different conformational families of pyrimidine·purine·pyrimidine triple helices depending on backbone composition ; Nucleic Acids Research; Vol. 22; No. 14; 2837-2844; PMCID PMC308255; 10.1093/nar/22.14.2837
Staubli, Andrea B. and Dervan, Peter B. (1994) Sequence specificity of the non-natural pyrido[2,3-d]pyrimidine nucleoside in triple helix formation ; Nucleic Acids Research; Vol. 22; No. 13; 2637-2642; PMCID PMC308221; 10.1093/nar/22.13.2637
Han, Hogyu and Dervan, Peter B. (1994) Visualization of RNA tertiary struture by RNA-EDTA·Fe(II) autocleavage: Analysis of tRNAPhe with uridine-EDTA·Fe(II) at position 47 ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 91; No. 11; 4955-4959; PMCID PMC43908
Hacia, Joseph G. and Dervan, Peter B., et el. (1994) Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation ; Biochemistry; Vol. 33; No. 20; 6192-6200; 10.1021/bi00186a019
Hacia, Joseph G. and Wold, Barbara J., et el. (1994) Phosphorothioate oligonucleotide-directed triple helix formation ; Biochemistry; Vol. 33; No. 18; 5367-5369; 10.1021/bi00184a002
Oakley, Martha G. and Turnbull, Kenneth D., et el. (1994) Synthesis of a hybrid protein containing the iron-binding ligand of bleomycin and the DNA-binding domain of Hin ; Bioconjugate Chemistry; Vol. 5; No. 3; 242-247; 10.1021/bc00027a009
Mrksich, Milan and Dervan, Peter B. (1994) Design of a Covalent Peptide Heterodimer for Sequence-Specific Recognition in the Minor Groove of Double-Helical DNA ; Journal of the American Chemical Society; Vol. 116; No. 8; 3663-3664; 10.1021/ja00087a088
Geierstanger, Bernhard H. and Jacobsen, Jens Peter, et el. (1994) Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA ; Biochemistry; Vol. 33; No. 10; 3055-3062; 10.1021/bi00176a039
Colocci, Natalia and Dervan, Peter B. (1994) Cooperative Binding of 8-mer Oligonucleotides Containing 5-(1-Propynyl)-2'-deoxyuridine to Adjacent DNA Sites by Triple-Helix Formation ; Journal of the American Chemical Society; Vol. 116; No. 2; 785-786; 10.1021/ja00081a056
Singleton, Scott F. and Dervan, Peter B. (1993) Equilibrium association constants for oligonucleotide-directed triple helix formation at single DNA sites: linkage to cation valence and concentration ; Biochemistry; Vol. 32; No. 48; 13171-13179; 10.1021/bi00211a028
Dwyer, Tammy J. and Geierstanger, Bernhard H., et el. (1993) Structural analysis of covalent peptide dimers, bis(pyridine-2-carboxamidonetropsin)(CH_2)_(3-6), in complex with 5'-TGACT-3' sites by two-dimensional NMR ; Journal of the American Chemical Society; Vol. 115; No. 22; 9900-9906; 10.1021/ja00075a005
Mrksich, Milan and Dervan, Peter B. (1993) Enhanced sequence specific recognition in the minor groove of DNA by covalent peptide dimers: bis(pyridine-2-carboxamidonetropsin)(CH_2)_(3-6) ; Journal of the American Chemical Society; Vol. 115; No. 22; 9892-9899; 10.1021/ja00075a004
Radhakrishnan, Ishwar and Patel, Dinshaw J., et el. (1993) NMR structural studies on a nonnatural deoxyribonucleoside which mediates recognition of GC base pairs in pyrimidine•purine•pyrimidine DNA triplexes ; Biochemistry; Vol. 32; No. 41; 11228-11234; 10.1021/bi00092a037
Koshlap, Karl M. and Gillespie, Paul, et el. (1993) Nonnatural deoxyribonucleoside D_3 incorporated in an intramolecular DNA triplex binds sequence-specifically by intercalation ; Journal of the American Chemical Society; Vol. 115; No. 17; 7908-7909; 10.1021/ja00070a059
Feng, Jin-An and Simon, Melvin, et el. (1993) Crystallization and preliminary X-ray analysis of the DNA binding domain of the Hin recombinase with its DNA binding site ; Journal of Molecular Biology; Vol. 232; No. 3; 982-986; 10.1006/jmbi.1993.1443
Colocci, Natalia and Distefano, Mark D., et el. (1993) Cooperative oligonucleotide-directed triple helix formation at adjacent DNA sites ; Journal of the American Chemical Society; Vol. 115; No. 11; 4468-4473; 10.1021/ja00064a008
Tor, Yitzhak and Dervan, Peter B. (1993) Site-specific enzymic incorporation of an unnatural base, N^6-(6-aminohexyl)isoguanosine, into RNA ; Journal of the American Chemical Society; Vol. 115; No. 11; 4461-4467; 10.1021/ja00064a007
Han, Hogyu and Dervan, Peter B. (1993) Sequence-specific recognition of double helical RNA and RNA·DNA by triple helix formation ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 90; No. 9; 3806-3810; PMCID PMC46394; 10.1073/pnas.90.9.3806
Mrksich, Milan and Dervan, Peter B. (1993) Antiparallel side-by-side heterodimer for sequence-specific recognition in the minor groove of DNA by a distamycin/1-methylimidazole-2-carboxamide-netropsin pair ; Journal of the American Chemical Society; Vol. 115; No. 7; 2572-2576; 10.1021/ja00060a004
MacDonald, Marcy E. and Strobel, Scott A., et el. (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ; Cell; Vol. 72; No. 6; 971-83; 10.1016/0092-8674(93)90585-E
Stilz, Hans Ulrich and Dervan, Peter B. (1993) Specific recognition of CG base pairs by 2-deoxynebularine within the purine•purine•pyrimidine triple-helix motif ; Biochemistry; Vol. 32; No. 9; 2177-85; 10.1021/bi00060a008
Distefano, Mark D. and Dervan, Peter B. (1993) Energetics of Cooperative Binding of Oligonucleotides with Discrete Dimerization Domains to DNA by Triple Helix Formation ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 90; No. 4; 1179-1183; PMCID PMC45836; 10.1073/pnas.90.4.1179
Distefano, Mark D. and Dervan, Peter B. (1992) Ligand-promoted dimerization of oligonucleotides binding cooperatively to DNA ; Journal of the American Chemical Society; Vol. 114; No. 27; 11006-11007; 10.1021/ja00053a073
Oakley, Martha G. and Mrksich, Milan, et el. (1992) Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNA ; Biochemistry; Vol. 31; No. 45; 10969-10975; 10.1021/bi00160a005
Wade, Warren S. and Mrksich, Milan, et el. (1992) Design of peptides that bind in the minor groove of DNA at 5'-(A,T)G(A,T)C(A,T)-3' sequences by a dimeric side-by-side motif ; Journal of the American Chemical Society; Vol. 114; No. 23; 8783-8794; 10.1021/ja00049a006
Singleton, Scott F. and Dervan, Peter B. (1992) Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites ; Biochemistry; Vol. 31; No. 45; 10995-11003; 10.1021/bi00160a008
Griffin, Linda C. and Kiessling, Laura L., et el. (1992) Recognition of all four base pairs of double-helical DNA by triple-helix formation: design of nonnatural deoxyribonucleosides for pyrimidine•purine base pair binding ; Journal of the American Chemical Society; Vol. 114; No. 21; 7976-7982; 10.1021/ja00047a003
Mack, David P. and Dervan, Peter B. (1992) Sequence-specific oxidative cleavage of DNA by a designed metalloprotein, nickel(II)•GGH(Hin139-190) ; Biochemistry; Vol. 31; No. 39; 9399-405; 10.1021/bi00154a011
Dervan, Peter B. (1992) Reagents for the site-specific cleavage of megabase DNA ; Nature; Vol. 359; No. 6390; 87-88; 10.1038/359087a0
Singleton, Scott F. and Dervan, Peter B. (1992) Thermodynamics of oligodeoxyribonucleotide-directed triple helix formation: an analysis using quantitative affinity cleavage titration ; Journal of the American Chemical Society; Vol. 114; No. 18; 6957-6965; 10.1021/ja00044a002
Mrksich, Milan and Wade, Warren S., et el. (1992) Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2 carboxamide netropsin ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 16; 7586-7590; PMCID PMC49755; 10.1073/pnas.89.16.7586
Povsic, Thomas J. and Strobel, Scott A., et el. (1992) Sequence-specific double-strand alkylation and cleavage of DNA mediated by triple-helix formation ; Journal of the American Chemical Society; Vol. 114; No. 15; 5934-5941; 10.1021/ja00041a005
Luebke, Kevin J. and Dervan, Peter B. (1992) Nonenymatic ligation of double-helical DNA by alternate-strand triple helix formation ; Nucleic Acids Research; Vol. 20; No. 12; 3005-3009; PMCID PMC312430; 10.1093/nar/20.12.3005
Beal, Peter A. and Dervan, Peter B. (1992) Recognition of double helical DNA by alternate strand triple helix formation ; Journal of the American Chemical Society; Vol. 114; No. 13; 4976-4982; 10.1021/ja00039a004
Beal, Peter A. and Dervan, Peter B. (1992) The influence of single base triplet changes on the stability of a Pur·Pur·Pyr triple helix determined by affinity cleaving ; Nucleic Acids Research; Vol. 20; No. 11; 2773-2776; PMCID PMC336921; 10.1093/nar/20.11.2773
Kiessling, Laura L. and Griffin, Linda C., et el. (1992) Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving ; Biochemistry; Vol. 31; No. 10; 2829-2834; 10.1021/bi00125a026
Koh, Jong Sung and Dervan, Peter B. (1992) Design of a nonnatural deoxyribonucleoside for recognition of GC base pairs by oligonucleotide-directed triple helix formation ; Journal of the American Chemical Society; Vol. 114; No. 4; 1470-1478; 10.1021/ja00030a050
Maher, L. James, III and Dervan, Peter B., et el. (1992) Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system ; Biochemistry; Vol. 31; No. 1; 70-81; 10.1021/bi00116a012
Strobel, Scott A. and Doucette-Stamm, Lynn A., et el. (1991) Site-specific cleavage of human chromosome 4 mediated by triple-helix formation ; Science; Vol. 254; No. 5038; 1639-1642; 10.1126/science.1836279
Shin, Jumi A. and Ebright, Richard H., et el. (1991) Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving ; Nucleic Acids Research; Vol. 19; No. 19; 5233-5236; PMCID PMC328881; 10.1093/nar/19.19.5233
Horne, David A. and Dervan, Peter B. (1991) Effects of an abasic site on triple helix formation characterized by affinity cleaving ; Nucleic Acids Research; Vol. 19; No. 18; 4963-4965; PMCID PMC328797; 10.1093/nar/19.18.4963
Luebke, Kevin J. and Dervan, Peter B. (1991) Nonenzymic sequence-specific ligation of double-helical DNA ; Journal of the American Chemical Society; Vol. 113; No. 19; 7447-7448; 10.1021/ja00019a066
Distefano, Mark D. and Shin, Jumi A., et el. (1991) Cooperative binding of oligonucleotides to DNA by triple helix formation: dimerization via Watson-Crick hydrogen bonds ; Journal of the American Chemical Society; Vol. 113; No. 15; 5901-5902; 10.1021/ja00015a076
Beal, Peter A. and Dervan, Peter B. (1991) Second Structural Motif for Recognition of DNA by Oligonucleotide-Directed Triple-Helix Formation ; Science; Vol. 251; No. 4999; 1360-1363; 10.1126/science.2003222
Strobel, Scott A. and Dervan, Peter B. (1991) Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation ; Nature; Vol. 350; No. 6314; 172-174; 10.1038/350172a0
Povsic, Thomas J. and Dervan, Peter B. (1990) Sequence-specific alkylation of double-helical DNA by oligonucleotide-directed triple-helix formation ; Journal of the American Chemical Society; Vol. 112; No. 25; 9428-9430; 10.1021/ja00181a075
Plum, G. Eric and Park, Young-Whan, et el. (1990) Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: A spectroscopic and calorimetric study ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 87; No. 23; 9436-9440; PMCID PMC55180; 10.1073/pnas.87.23.9436
Häner, Robert and Dervan, Peter B. (1990) Single-strand DNA triple-helix formation ; Biochemistry; Vol. 29; No. 42; 9761-9765; 10.1021/bi00494a001
Graham, Kenneth S. and Dervan, Peter B. (1990) Structural motif of the DNA binding domain of γδ-resolvase characterized by affinity cleaving ; Journal of Biological Chemistry; Vol. 265; No. 27; 16534-16540
Maher, L. James, III and Dervan, Peter B., et el. (1990) Kinetic analysis of oligodeoxyribonucleotide-directed triple-helix formation on DNA ; Biochemistry; Vol. 29; No. 37; 8820-8826; 10.1021/bi00489a045
Sluka, James P. and Griffin, John H., et el. (1990) Reagents and methods for the solid-phase synthesis of protein-EDTA for use in affinity cleaving ; Journal of the American Chemical Society; Vol. 112; No. 17; 6369-6374; 10.1021/ja00173a027
Sluka, James P. and Horvath, Suzanna J., et el. (1990) Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinase ; Biochemistry; Vol. 29; No. 28; 6551-6561; 10.1021/bi00480a002
Mack, David P. and Sluka, James P., et el. (1990) Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix site ; Biochemistry; Vol. 29; No. 28; 6561-6567; 10.1021/bi00480a003
Strobel, Scott A. and Dervan, Peter B. (1990) Site-Specific Cleavage of a Yeast Chromosome by Oligonucleotide-Directed Triple-Helix Formation ; Science; Vol. 249; No. 4964; 73-75; 10.1126/science.2195655
Mack, David P. and Dervan, Peter B. (1990) Nickel-mediated sequence-specific oxidative cleavage of DNA by a designed metalloprotein ; Journal of the American Chemical Society; Vol. 112; No. 11; 4604-4606; 10.1021/ja00167a102
Oakley, Martha G. and Dervan, Peter B. (1990) Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving ; Science; Vol. 248; No. 4957; 847-850; 10.1126/science.2111578
Horne, David A. and Dervan, Peter B. (1990) Recognition of mixed-sequence duplex DNA by alternate-strand triple-helix formation ; Journal of the American Chemical Society; Vol. 112; No. 6; 2435-2437; 10.1021/ja00162a063
Luebke, Kevin J. and Dervan, Peter B. (1989) Nonenzymatic ligation of oligodeoxyribonucleotides on a duplex DNA template by triple-helix formation ; Journal of the American Chemical Society; Vol. 111; No. 23; 8733-8735; 10.1021/ja00205a033
Griffin, Linda C. and Dervan, Peter B. (1989) Recognition of Thymine Adenine Base Pairs by Guanine in a Pyrimidine Triple Helix Motif ; Science; Vol. 245; No. 4921; 967-971; 10.1126/science.2549639
Strobel, Scott A. and Dervan, Peter B. (1989) Cooperative site specific binding of oligonucleotides to duplex DNA ; Journal of the American Chemical Society; Vol. 111; No. 18; 7286-7287; 10.1021/ja00200a073
Maher, Louis J., III and Wold, Barbara, et el. (1989) Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation ; Science; Vol. 245; No. 4919; 725-730; 10.1126/science.2549631
Wang, Andrew H.-J. and Cottens, Sylvain, et el. (1989) Interactions between a symmetrical minor groove binding compound and DNA oligonucleotides: ^1H and ^(19)F NMR studies ; Journal of Biomolecular Structure and Dynamics; Vol. 7; No. 1; 101-117; 10.1080/07391102.1989.10507754
Martello, Pamela A. and Bruzik, James P., et el. (1989) Specific activation of open complex formation at an Escherichia coli promoter by oligo(N-methylpyrrolecarboxamide)s: effects of peptide length and identification of DNA target sites ; Biochemistry; Vol. 28; No. 10; 4455-61; 10.1021/bi00436a050
Povsic, Thomas J. and Dervan, Peter B. (1989) Triple helix formation by oligonucleotides on DNA extended to the physiological pH range ; Journal of the American Chemical Society; Vol. 111; No. 8; 3059-3061; 10.1021/ja00190a047
Baker, Brenda F. and Dervan, Peter B. (1989) Sequence-specific cleavage of DNA by N-bromoacetyldistamycin. Product and kinetic analyses ; Journal of the American Chemical Society; Vol. 111; No. 7; 2700-2712; 10.1021/ja00189a054
Strobel, Scott A. and Moser, Heinz E., et el. (1988) Double strand cleavage of genomic DNA at a single site by triple helix formation ; Journal of the American Chemical Society; Vol. 110; No. 23; 7927-7929; 10.1021/ja00231a082
Mack, David P. and Iverson, Brent L., et el. (1988) Design and chemical synthesis of a sequence-specific DNA-cleaving protein ; Journal of the American Chemical Society; Vol. 110; No. 22; 7572-7574; 10.1021/ja00230a067
Iverson, Brent L. and Dervan, Peter B. (1988) Nonenzymatic sequence-specific methyl transfer to single-stranded DNA ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 13; 4615-4619; PMCID PMC280485
Dervan, Peter B. (1988) John D. Roberts ; Aldrichimica Acta; Vol. 21; No. 3; 71-77
Youngquist, R. Scott and Dervan, Peter B. (1987) A synthetic peptide binds 16 base pairs of A,T double helical DNA ; Journal of the American Chemical Society; Vol. 109; No. 24; 7564-7566; 10.1021/ja00258a070
Sluka, James P. and Horvath, Suzanna J., et el. (1987) Synthesis of a sequence-specific DNA-cleaving peptide ; Science; Vol. 238; No. 4830; 1129-1132; 10.1126/science.3120311
Moser, Heinz E. and Dervan, Peter B. (1987) Sequence-specific cleavage of double helical DNA by triple helix formation ; Science; Vol. 238; No. 4827; 645-650; 10.1126/science.3118463
Griffin, John H. and Dervan, Peter B. (1987) Metalloregulation in the sequence specific binding of synthetic molecules to DNA ; Journal of the American Chemical Society; Vol. 109; No. 22; 6840-6842; 10.1021/ja00256a043
Iverson, Brent L. and Dervan, Peter B. (1987) Adenine specific DNA chemical sequencing reaction ; Nucleic Acids Research; Vol. 15; No. 19; 7823-7830; PMCID PMC306310; 10.1093/nar/15.19.7823
Joran, A. D. and Leland, B. A., et el. (1987) Effect of exothermicity on electron transfer rates in photosynthetic molecular models ; Nature; Vol. 327; No. 6122; 508-511; 10.1038/327508a0
Wade, Warren S. and Dervan, Peter B. (1987) Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide ; Journal of the American Chemical Society; Vol. 109; No. 5; 1574-1575; 10.1021/ja00239a050
Iverson, Brent L. and Dervan, Peter B. (1987) Nonenzymatic sequence-specific cleavage of single-stranded DNA to nucleotide resolution. DNA methyl thioether probes ; Journal of the American Chemical Society; Vol. 109; No. 4; 1241-1243; 10.1021/ja00238a041
Mendel, David and Dervan, Peter B. (1987) Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 84; No. 4; 910-914; PMCID PMC304329
Griffin, John H. and Dervan, Peter B. (1986) Sequence-specific recognition of right-handed double-helical DNA by (2S,3S)- and (2R,3R)-dihydroxybis(netropsin)succinamide ; Journal of the American Chemical Society; Vol. 108; No. 16; 5008-5009; 10.1021/ja00276a052
Dervan, Peter B. and Baker, Brenda F. (1986) Design of sequence-specific DNA cleaving molecules: Comparison of distamycin-EDTA • Fe(II) and N-bromoacetyldistamycin ; Annals of the New York Academy of Sciences; Vol. 471; 51-59; 10.1111/j.1749-6632.1986.tb48025.x
Dervan, Peter B. (1986) Design of Sequence-Specific DNA-Binding Molecules ; Science; Vol. 232; No. 4749; 464-471; 10.1126/science.2421408
Baker, Brenda F. and Dervan, Peter B. (1985) Sequence-specific cleavage of double-helical DNA. N-Bromoacetyldistamycin ; Journal of the American Chemical Society; Vol. 107; No. 26; 8266-8268; 10.1021/ja00312a079
Leland, B. A. and Joran, A. D., et el. (1985) Picosecond Fluorescence Studies on Intramolecular Photochemical Electron Transfer in Porphyrins Linked to Quinones at Two Different Fixed Distances ; Journal of Physical Chemistry; Vol. 89; No. 26; 5571-5573; 10.1021/j100272a002
Berger, Carole L. and Cantor, Charles, et el. (1985) Comparison of synthetic psoralen derivatives and 8-MOP in the inhibition of lymphocyte proliferation ; Annals of the New York Academy of Sciences; Vol. 453; 80-90; 10.1111/j.1749-6632.1985.tb11800.x
Youngquist, R. Scott and Dervan, Peter B. (1985) Sequence-specific recognition of B DNA by bis(EDTA-distamycin)fumaramide ; Journal of the American Chemical Society; Vol. 107; No. 19; 5528-5529; 10.1021/ja00305a036
Harshman, Keith D. and Dervan, Peter B. (1985) Molecular recognition of B-DNA by Hoechst 33258 ; Nucleic Acids Research; Vol. 13; No. 13; 4825-4835; PMCID PMC321829; 10.1093/nar/13.13.4825
Youngquist, R. Scott and Dervan, Peter B. (1985) Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 82; No. 9; 2565-2569; PMCID PMC397604
Dreyer, Geoffrey B. and Dervan, Peter B. (1985) Sequence-specific cleavage of single-stranded DNA: Oligodeoxynucleotide-EDTA·Fe(II) ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 82; No. 4; 968-972; PMCID PMC397174
Joran, Alvin D. and Leland, Burt A., et el. (1984) Models for photochemical electron transfer at fixed distances. Porphyrin-bicyclo[2.2.2]octane-quinone and porphyrin-bisbicyclo[2.2.2]octane-quinone ; Journal of the American Chemical Society; Vol. 106; No. 20; 6090-6092; 10.1021/ja00332a062
Van Dyke, Michael M. and Dervan, Peter B. (1984) Echinomycin Binding Sites on DNA ; Science; Vol. 225; No. 4667; 1122-1127; 10.1126/science.6089341
Hertzberg, Robert P. and Dervan, Peter B. (1984) Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses ; Biochemistry; Vol. 23; No. 17; 3934-3945; 10.1021/bi00312a022
Sylwester, Alan P. and Dervan, Peter B. (1984) Low-temperature matrix isolation of the 1,1-diazene H_2NN. Electronic and infrared characterization ; Journal of the American Chemical Society; Vol. 106; No. 16; 4648-4650; 10.1021/ja00328a076
Schultz, Peter G. and Dervan, Peter B. (1984) Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving ; Journal of Biomolecular Structure and Dynamics; Vol. 1; No. 5; 1133-1147; 10.1080/07391102.1984.10507508
Taylor, John S. and Schultz, Peter G., et el. (1984) DNA affinity cleaving : Sequence specific cleavage of DNA by Distamycin-EDTA • Fe(II) and EDTA-distamycin • Fe(II) ; Tetrahedron; Vol. 40; No. 3; 457-465; 10.1016/0040-4020(84)85050-4
Schultz, P. G. and Dervan, P. B. (1983) Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin•Fe^(II)) and EDTA-bis(distamycin)•Fe^(II) ; Journal of the American Chemical Society; Vol. 105; No. 26; 7748-7750; 10.1021/ja00364a049
Schultz, Peter G. and Dervan, Peter B. (1983) Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA·Fe(II) ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 22; 6834-6837; PMCID PMC390080
Van Dyke, Michael W. and Dervan, Peter B. (1983) Methidiumpropyl-EDTA•Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA ; Nucleic Acids Research; Vol. 11; No. 16; 5555-5567; PMCID PMC326297; 10.1093/nar/11.16.5555
Cartwright, Iain L. and Hertzberg, Robert P., et el. (1983) Cleavage of chromatin with methidiumpropyl-EDTA·iron(II) ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 11; 3213-3217; PMCID PMC394010
Van Dyke, Michael W. and Dervan, Peter B. (1983) Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous DNA. Footprinting with methidiumpropyl-EDTA•iron(II) ; Biochemistry; Vol. 22; No. 10; 2373-2377; 10.1021/bi00279a011
Duan, Daniel C. and Dervan, Peter B. (1983) Evidence for a stereospecific 1,2-elimination reaction in a 1,1-diazene. Synthesis and decomposition of [N-phenyl(threo- and erythro)-2-deuterio-1-methylpropyl)amino]nitrene ; Journal of Organic Chemistry; Vol. 48; No. 7; 970-976; 10.1021/jo00155a008
Van Dyke, M. W. and Dervan, P. B. (1983) Footprinting with MPE·Fe(II). Complementary-strand Analyses of Distamycin- and Actinomycin-binding Sites on Heterogeneous DNA ; Cold Spring Harbor Symposia on Quantitative Biology; Vol. 47; No. Pt 1; 347-353; 10.1101/SQB.1983.047.01.040
Van Dyke, M. W. and Dervan, P. B. (1983) Footprinting with MPE•Fe(II). Complementary-strand analyses of distamycin- and actinomycin-binding sites on heterogeneous DNA ; Cold Spring Harbor Symposia on Quantitative Biology; Vol. 47; 347-353; 10.1101/SQB.1983.047.01.040
Schultz, Peter G. and Dervan, Peter B. (1982) Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene ; Journal of the American Chemical Society; Vol. 104; No. 24; 6660-6668; 10.1021/ja00388a031
Schultz, Peter G. and Taylor, John S., et el. (1982) Design synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II) ; Journal of the American Chemical Society; Vol. 104; No. 24; 6861-6863; 10.1021/ja00388a101
McIntyre, Daniel K. and Dervan, Peter B. (1982) 1,1-Di-tert-butyldiazene ; Journal of the American Chemical Society; Vol. 104; No. 23; 6466-6468; 10.1021/ja00387a061
Van Dyke, Michael W. and Hertzberg, Robert P., et el. (1982) Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA·Fe(II) ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 79; No. 18; 5470-5474; PMCID PMC346925
Mitchell, Mark A. and Dervan, Peter B. (1982) Interhelical DNA-DNA crosslinking. Bis(monoazidomethidium)octaoxahexacosanediamine: a probe of packaged nucleic acid ; Journal of the American Chemical Society; Vol. 104; No. 15; 4265-4266; 10.1021/ja00379a045
Hinsberg, William D., III and Schultz, Peter G., et el. (1982) Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene ; Journal of the American Chemical Society; Vol. 104; No. 3; 766-773; 10.1021/ja00367a020
Ikeda, Richard A. and Dervan, Peter B. (1982) Sequence-selective inhibition of restriction endonucleases by the polyintercalator bis(methidium)spermine ; Journal of the American Chemical Society; Vol. 104; No. 1; 296-297; 10.1021/ja00365a058
Hertzberg, Robert P. and Dervan, Peter B. (1982) Cleavage of double helical DNA by methidium-propyl-EDTA-iron(II) ; Journal of the American Chemical Society; Vol. 104; No. 1; 313-315; 10.1021/ja00365a069
Dervan, Peter B. and Squillacote, Michael E., et el. (1981) ^(15)N NMR Spectrum of a 1,1-Diazene. N-(2,2,6,6-Tetramethylpiperidyl)nitrene ; Journal of the American Chemical Society; Vol. 103; No. 5; 1120-1122; 10.1021/ja00395a021
Schultz, Peter G. and Dervan, Peter B. (1981) Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene ; Journal of the American Chemical Society; Vol. 103; No. 6; 1563-1564; 10.1021/ja00396a048
Dervan, Peter B. and Santilli, Donald S. (1980) Synthesis and thermal decomposition of cis-3,4,5,6-tetrahydropyridazine-3,4-d2. Relative rates of rotation, cleavage, and closure for tetramethylene ; Journal of the American Chemical Society; Vol. 102; No. 11; 3863-3870; 10.1021/ja00531a031
Schultz, Peter G. and Dervan, Peter B. (1980) Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. Comparison of five- and six-membered cyclic 1,1-dialkyldiazenes ; Journal of the American Chemical Society; Vol. 102; No. 2; 878-880; 10.1021/ja00522a090
Hinsberg, William D., III and Dervan, Peter B. (1979) Kinetics of the thermal decomposition of a 1,1-dialkyldiazene, N-(2,2,6,6-tetramethylpiperidyl)nitrene ; Journal of the American Chemical Society; Vol. 101; No. 20; 6142-6144; 10.1021/ja00514a058
Dervan, Peter B. and Jones, Carol R. (1979) Syntheses and Decomposition of meso- and dl-2,3-Dimethylsuccinyl and cis- and trans-1,2-Hexahydrophthaloyl Peroxides ; Journal of Organic Chemistry; Vol. 44; No. 13; 2116-2123; 10.1021/jo01327a016
Santilli, Donald S. and Dervan, Peter B. (1979) Thermal decomposition of cis-tetrahydropyridazine-3,4-d_2. Relative rates of rotation, cleavage, and closure for tetramethylene ; Journal of the American Chemical Society; Vol. 101; No. 13; 3663-3664; 10.1021/ja00507a045
Becker, Michael McClellan and Dervan, Peter B. (1979) Molecular recognition of nucleic acid by small molecules. Binding affinity and structural specificity of bis(methidium)spermine ; Journal of the American Chemical Society; Vol. 101; No. 13; 3664-3666; 10.1021/ja00507a046
Dervan, Peter B. and Uyehara, Tadao (1979) Stereochemical tests of cyclic 1,1-dialkyldiazene fragmentation reactions. Thermal decomposition of N-(cis-(and trans-)2,3-(and 2,5-)dimethylpyrrolidine)nitrenes ; Journal of the American Chemical Society; Vol. 101; No. 8; 2076-2082; 10.1021/ja00502a023
Dervan, Peter B. and Uyehara, Tadao, et el. (1979) Experimental determination of the relative rates of rotation, cleavage, closure, and 1,5-hydrogen shift for 3-methyl-1,4-pentanediyl. Evidence for 1,4 biradicals as common intermediates from different precursors, 3,4-(and 3,6-)dimethyl-3,4,5,6-tetrahydropyridazines and 1,2-dimethylcyclobutanes ; Journal of the American Chemical Society; Vol. 101; No. 8; 2069-2075; 10.1021/ja00502a022
Dervan, Peter B. and Becker, Michael M. (1978) Molecular recognition of DNA by small molecules. Synthesis of bis(methidium)spermine, a DNA polyintercalating molecule ; Journal of the American Chemical Society; Vol. 100; No. 6; 1968-1970; 10.1021/ja00474a075
Hinsberg, William D., III and Dervan, Peter B. (1978) Synthesis and direct spectroscopic observation of a 1,1-dialkyldiazene. Infrared and electronic spectrum of N-(2,2,6,6-tetramethylpiperidyl)nitrene ; Journal of the American Chemical Society; Vol. 100; No. 5; 1608-1610; 10.1021/ja00473a051
Jones, Carol R. and Dervan, Peter B. (1977) Six-membered cyclic diacyl peroxide fragmentations. Thermal decomposition of meso- and dl-2,3-dimethylsuccinoyl peroxides ; Journal of the American Chemical Society; Vol. 99; No. 20; 6772-6774; 10.1021/ja00462a058
Shippey, Michael A. and Dervan, Peter B. (1977) Trimethylsilyl anions. Direct synthesis of trimethylsilylbenzenes ; Journal of Organic Chemistry; Vol. 42; No. 15; 2654-2655; 10.1021/jo00435a037
Berson, Jerome A. and Dervan, Peter B., et el. (1976) Formation and thermal rearrangements of some dimers of butadiene and piperylene. Tests of the validity of thermochemical-kinetic arguments for identification of common biradical intermediates ; Journal of the American Chemical Society; Vol. 98; No. 19; 5937-5968; 10.1021/ja00435a031
Dervan, Peter B. and Uyehara, Tadao (1976) A stereochemical test of similarly substituted tetramethylenediazene and cyclic azo decompositions in the gas phase at the same temperature ; Journal of the American Chemical Society; Vol. 98; No. 7; 2003-2005; 10.1021/ja00423a078
Dervan, Peter B. and Uyehara, Tadao (1976) Thermal decomposition of cis- and trans-3,4- and -3,6-dimethyl-3,4,5,6-tetrahydropyridazines. Evidence against the hot diradical postulate for azo decompositions ; Journal of the American Chemical Society; Vol. 98; No. 5; 1262-1264; 10.1021/ja00421a037
Dervan, Peter B. and Shippey, Michael A. (1976) Trimethylsilylpotassium. Deoxygenation of epoxides with inversion of stereochemistry ; Journal of the American Chemical Society; Vol. 98; No. 5; 1265-1267; 10.1021/ja00421a039
Dervan, Peter B. and Uyehara, Tadao (1976) 7-Azabicyclo[2.2.1]heptane N-Imide as an Intermediate in the Thermal Decomposition of N-Amino-7-Azabicyclo[2.2.1]heptane and the Corresponding Benzenesulphonamide ; Journal of the Chemical Society. Chemical Communications; Vol. 1976; No. 12; 469-470; 10.1039/C39760000469
Berson, Jerome A. and Dervan, Peter B. (1973) Mechanistic analysis of the four pathways in the 1,3-sigmatropic rearrangements of trans-1,2-trans, trans- and trans-1,2-cis,trans-dipropenylcyclobutane ; Journal of the American Chemical Society; Vol. 95; No. 1; 269-270; 10.1021/ja00782a062
Berson, Jerome A. and Dervan, Peter B. (1973) Rearrangement of trans-1,2-divinylcyclobutane and the energy surface of the dimers of butadiene ; Journal of the American Chemical Society; Vol. 95; No. 1; 267-269; 10.1021/ja00782a061
Berson, Jerome A. and Dervan, Peter B. (1972) Stereodistal Cope rearrangement of trans-1,2-dialkenylcyclobutanes ; Journal of the American Chemical Society; Vol. 94; No. 25; 8949-8950; 10.1021/ja00780a074
Berson, Jerome A. and Dervan, Peter B. (1972) Incremental substituent effects leading to steric blockade of the boat-like six-center Cope rearrangement of cis-1,2-dialkenylcyclobutanes ; Journal of the American Chemical Society; Vol. 94; No. 21; 7597-7598; 10.1021/ja00776a064
Berson, Jerome A. and Dervan, Peter B., et el. (1972) Stereospecific double rearrangement of trans-3,4-dimethyl-cis,trans-cycloocta-1,5-diene to cis-3,4-dimethyl-cis,cis-cycloocta-1,5-diene ; Journal of the American Chemical Society; Vol. 94; No. 21; 7598-7599; 10.1021/ja00776a065
Bennett, O. Francis and Bouchard, M. J., et el. (1972) Hydroxide displacement of the sulfone linkage in thioxanthen-9-one 10,10-dioxides to benzophenone-2'-hydroxy-2-sulfinic acids. Intramolecular cyclization to xanthones ; Journal of Organic Chemistry; Vol. 37; No. 9; 1356-1359; 10.1021/jo00974a015