@article{https://authors.library.caltech.edu/records/mbrmj-h6e60, title = "Peripheral neuronal activation shapes the microbiome and alters gut physiology", journal = "Cell Reports", year = "2024", url = "https://authors.library.caltech.edu/records/mbrmj-h6e60", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2024.113953", volume = "43", pmcid = "PMC11132177" } @article{https://authors.library.caltech.edu/records/nyxge-gz849, title = "Fast, accurate ranking of engineered proteins by target-binding propensity using structure modeling", journal = "Molecular Therapy", year = "2024", url = "https://authors.library.caltech.edu/records/nyxge-gz849", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2024.04.003" } @other{https://authors.library.caltech.edu/records/8b5yj-sjn05, title = "Synthetic dosage-compensating miRNA circuits allow precision gene therapy for Rett syndrome", journal = "bioRxiv", year = "2024", url = "https://authors.library.caltech.edu/records/8b5yj-sjn05", id = "record", issn = "2692-8205", doi = "10.1101/2024.03.13.584179", pmcid = "PMC10980028" } @article{https://authors.library.caltech.edu/records/1e7my-z6t94, title = "Immediate responses to ambient light in vivo reveal distinct subpopulations of suprachiasmatic VIP neurons", journal = "iScience", year = "2023", url = "https://authors.library.caltech.edu/records/1e7my-z6t94", id = "record", issn = "2589-0042", doi = "10.1016/j.isci.2023.107865", volume = "26", pmcid = "PMC10520357" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230725-857203000.51, title = "Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain", journal = "Nature Nanotechnology", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-857203000.51", id = "record", issn = "1748-3387", doi = "10.1038/s41565-023-01419-x", volume = "18", pmcid = "PMC10575780" } @article{https://authors.library.caltech.edu/records/sxje4-sj785, title = "Characterization and quantification of adeno-associated virus capsid-loading states by multi-wavelength analytical ultracentrifugation with UltraScan", journal = "Nanomedicine", year = "2023", url = "https://authors.library.caltech.edu/records/sxje4-sj785", id = "record", issn = "1743-5889", doi = "10.2217/nnm-2023-0156", volume = "18", pmcid = "PMC10652292" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230301-701033500.22, title = "Spatial transcriptomics for profiling the tropism of viral vectors in tissues", journal = "Nature Biotechnology", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230301-701033500.22", id = "record", issn = "1087-0156", doi = "10.1038/s41587-022-01648-w", volume = "41", pmcid = "PMC10443732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230615-129198000.12, title = "Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates", journal = "Nature Communications", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230615-129198000.12", id = "record", issn = "2041-1723", doi = "10.1038/s41467-023-38582-7", volume = "14", pmcid = "PMC10250345" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230221-20005500.75, title = "Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue", journal = "Nature Biotechnology", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230221-20005500.75", id = "record", issn = "1087-0156", doi = "10.1038/s41587-023-01681-3", pmcid = "PMC9885914" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230602-251993000.57, title = "Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors", journal = "Science Advances", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230602-251993000.57", id = "record", issn = "2375-2548", doi = "10.1126/sciadv.adg6618", volume = "9", pmcid = "PMC10115422" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230725-706045000.29, title = "Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system", journal = "Current Research in Neurobiology", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-706045000.29", id = "record", issn = "2665-945X", doi = "10.1016/j.crneur.2023.100086", volume = "4", pmcid = "PMC10313870" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230525-772152300.6, title = "CRISPR-clear imaging of melanin-rich B16-derived solid tumors", journal = "Communications Biology", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230525-772152300.6", id = "record", issn = "2399-3642", doi = "10.1038/s42003-023-04614-7", volume = "6", pmcid = "PMC10073193" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20230316-182564000.42, title = "Primate-conserved Carbonic Anhydrase IV and murine-restricted Ly6c1 are new targets for crossing the blood-brain barrier", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230316-182564000.42", id = "record", doi = "10.1101/2023.01.12.523632" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20230316-182523000.38, title = "Fast, accurate ranking of engineered proteins by receptor binding propensity using structural modeling", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230316-182523000.38", id = "record", doi = "10.1101/2023.01.11.523680" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20230316-182562000.41, title = "Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230316-182562000.41", id = "record", doi = "10.1101/2023.01.12.523844" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20230316-182503000.37, title = "Dysregulated mammalian estrus cycle rescued by timed activation of VIP neurons in the circadian pacemaker and late afternoon light exposure", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230316-182503000.37", id = "record", doi = "10.1101/2023.01.14.524075" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221202-906989500.8, title = "A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice", journal = "eLife", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221202-906989500.8", id = "record", issn = "2050-084X", doi = "10.7554/elife.81453", volume = "11", pmcid = "PMC9668333" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221209-478595000.5, title = "Molecular basis of astrocyte diversity and morphology across the CNS in health and disease", journal = "Science", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221209-478595000.5", id = "record", issn = "0036-8075", doi = "10.1126/science.adc9020", volume = "378" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220816-373601000, title = "Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid", journal = "Molecular Therapy - Methods \& Clinical Development", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220816-373601000", id = "record", issn = "2329-0501", doi = "10.1016/j.omtm.2022.07.010", volume = "26", pmcid = "PMC9372736" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220801-544880000, title = "Structural basis of receptor usage by the engineered capsid AAV-PHP.eB", journal = "Molecular Therapy - Methods \& Clinical Development", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220801-544880000", id = "record", issn = "2329-0501", doi = "10.1016/j.omtm.2022.07.011", volume = "26", pmcid = "PMC9382559" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221116-602375500.16, title = "Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs", journal = "Biomaterials", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221116-602375500.16", id = "record", issn = "0142-9612", doi = "10.1016/j.biomaterials.2022.121701", volume = "288", pmcid = "PMC9621732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220606-735990000, title = "Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems", journal = "Neuron", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220606-735990000", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2022.05.003", volume = "110", pmcid = "PMC9308721" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20220706-965670000, title = "A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220706-965670000", id = "record", doi = "10.1101/2022.06.27.497828" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220525-90416000, title = "Adeno-Associated Virus Toolkit to Target Diverse Brain Cells", journal = "Annual Review of Neuroscience", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220525-90416000", id = "record", issn = "0147-006X", doi = "10.1146/annurev-neuro-111020-100834", volume = "45" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210709-224144084, title = "Age-dependent alterations in key components of the nigrostriatal dopaminergic system and distinct motor phenotypes", journal = "Acta Pharmacologica Sinica", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210709-224144084", id = "record", issn = "1671-4083", doi = "10.1038/s41401-021-00713-5", volume = "43", pmcid = "PMC8975991" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220104-157923000, title = "Glutamate in primary afferents is required for itch transmission", journal = "Neuron", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220104-157923000", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2021.12.007", volume = "110", pmcid = "PMC8898340" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210728-223917563, title = "Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice", journal = "Nature Biomedical Engineering", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210728-223917563", id = "record", issn = "2157-846X", doi = "10.1038/s41551-021-00759-0", volume = "6" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20220111-302458000, title = "Intravenous gene transfer throughout the brain of infant Old World primates using AAV", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220111-302458000", id = "record", doi = "10.1101/2022.01.08.475342" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20220104-249193900, title = "Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220104-249193900", id = "record", doi = "10.1101/2021.12.29.474408" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20211210-240709000, title = "AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset", journal = "Nature Neuroscience", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211210-240709000", id = "record", issn = "1097-6256", doi = "10.1038/s41593-021-00969-4", volume = "25" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210629-153450418, title = "Deep Parallel Characterization of AAV Tropism and AAV-Mediated Transcriptional Changes via Single-Cell RNA Sequencing", journal = "Frontiers in Immunology", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210629-153450418", id = "record", issn = "1664-3224", doi = "10.3389/fimmu.2021.730825", volume = "12", pmcid = "PMC8574206" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210930-210049351, title = "Improved systemic AAV gene therapy with a neurotrophic capsid in Niemann–Pick disease type C1 mice", journal = "Life Science Alliance", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210930-210049351", id = "record", issn = "2575-1077", doi = "10.26508/lsa.202101040", volume = "4", pmcid = "PMC8380657" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20211008-224633454, title = "Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses", journal = "Cell Reports", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211008-224633454", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2021.109744", volume = "36", pmcid = "PMC8552649" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200925-104734056, title = "Human embryo polarization requires PLC signaling to mediate trophectoderm specification", journal = "eLife", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200925-104734056", id = "record", issn = "2050-084X", doi = "10.7554/eLife.65068", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210625-220915439, title = "Specific and behaviorally consequential astrocyte G\_q GPCR signaling attenuation in vivo with iβARK", journal = "Neuron", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210625-220915439", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2021.05.023", volume = "109", pmcid = "PMC8418870" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210706-202344110, title = "Microbiota regulate social behaviour via stress response neurons in the brain", journal = "Nature", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210706-202344110", id = "record", issn = "0028-0836", doi = "10.1038/s41586-021-03669-y", volume = "595", pmcid = "PMC8346519" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210519-141318892, title = "The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210519-141318892", id = "record", issn = "0027-8424", doi = "10.1073/pnas.2017925118", volume = "118", pmcid = "PMC8166199" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210629-201655221, title = "Use of high-content imaging to quantify transduction of AAV-PHP viruses in the brain following systemic delivery", journal = "Brain Communications", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210629-201655221", id = "record", issn = "2632-1297", doi = "10.1093/braincomms/fcab105", volume = "3", pmcid = "PMC8200048" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200421-092814882, title = "Enhancer viruses for combinatorial cell-subclass-specific labeling", journal = "Neuron", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200421-092814882", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2021.03.011", volume = "109", pmcid = "PMC8610077" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210527-161220137, title = "Deep Tropism Profiling of Barcoded AAV Capsid and Cargo Pools in Intact Tissue Using High-Throughput Ultrasensitive Sequential FISH", journal = "Molecular Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210527-161220137", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210528-081450340, title = "Endothelial-Tropic AAVs for Genetic Access to Whole-Brain Vasculature in Wild-Type Mouse Strains Following Non-Invasive Systemic Delivery", journal = "Molecular Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210528-081450340", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210528-082042148, title = "Targeted Gene Therapy with Engineered Systemic AAVs for the Central and Peripheral Nervous Systems Prevents Motor Coordination Phenotypes in a Mouse Model of Friedreich's Ataxia", journal = "Molecular Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210528-082042148", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210527-160526973, title = "Simultaneous Detection of AAV Genome, Transcript, and Protein Localization in Intact Cells and Tissues at High Resolution", journal = "Molecular Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210527-160526973", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210428-094505098, title = "Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice", journal = "Science", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210428-094505098", id = "record", issn = "0036-8075", doi = "10.1126/science.abe1931", volume = "372", pmcid = "PMC8457366" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20210414-072514678, title = "Neuronal Activation of the Gastrointestinal Tract Shapes the Gut Environment in Mice", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210414-072514678", id = "record", doi = "10.1101/2021.04.12.439539" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200421-093728277, title = "Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex", journal = "Cell Reports", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200421-093728277", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2021.108754", volume = "34" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200728-094010838, title = "Dorsal Raphe Dopamine Neurons Signal Motivational Salience Dependent on Internal State, Expectation, and Behavioral Context", journal = "Journal of Neuroscience", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200728-094010838", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2690-20.2021", volume = "41", pmcid = "PMC8018733" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201217-143607354, title = "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning", journal = "Cell", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201217-143607354", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2020.11.040", volume = "183", pmcid = "PMC8025677" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200817-140210217, title = "Negative feedback control of neuronal activity by microglia", journal = "Nature", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200817-140210217", id = "record", issn = "0028-0836", doi = "10.1038/s41586-020-2777-8", volume = "586" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200810-121624161, title = "Expanding the brain researcher's toolkit", journal = "Science", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200810-121624161", id = "record", issn = "0036-8075", doi = "10.1126/science.abd2660", volume = "369" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20200626-103613335, title = "Broad gene expression throughout the mouse and marmoset brain after intravenous delivery of engineered AAV capsids", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-103613335", id = "record", doi = "10.1101/2020.06.16.152975" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200121-141523675, title = "Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types", journal = "Nature Methods", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200121-141523675", id = "record", issn = "1548-7091", doi = "10.1038/s41592-020-0799-7", volume = "17", pmcid = "PMC7219404" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200504-132509459, title = "Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation", journal = "Nature Communications", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200504-132509459", id = "record", issn = "2041-1723", doi = "10.1038/s41467-020-15818-4", volume = "11", pmcid = "PMC7193641" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-074008042, title = "Method for High-Throughput, In Situ Characterization of AAV Variant Pools in Intact Tissue Using Ultrasensitive Sequential FISH", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-074008042", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-073642424, title = "Targeting the Rodent Peripheral Nervous System Efficiently and with Greater Specificity through Intravenous Delivery of AAV Capsids Evolved by Multiplexed-CREATE", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-073642424", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-083821035, title = "Evolution and Investigation of Engineered AAV Capsids Exhibiting Enhanced Transduction of the Central Nervous System with or without Murine Strain Specificity", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-083821035", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-094818518, title = "Recombinant AAVs Target Custom Frataxin Therapeutic Cassettes to Tissues of Pathophysiologic Relevance in Friedreich's Ataxia", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-094818518", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-073231089, title = "Cloud-based Software for NGS Data Management and Analysis for Directed Evolution of Peptide-Based Delivery Vectors", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-073231089", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-134728909, title = "Building a Toolbox of Compact Enhancers for Cell Type-Specific Gene Expression from AAVs in the Primate Brain", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-134728909", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-075354300, title = "In-Depth Parallel Profiling of Tissue and Cell-Type Tropism of AAV Variants by Single-Cell RNA Sequencing", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-075354300", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-154158513, title = "Transduction Profiles of Engineered Adeno-Associated Viral Capsids in Mouse and Marmoset", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-154158513", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-102237108, title = "A Computational and Experimental Platform for Detecting Full Transcriptome Cell Type Tropism of Lowly Expressed Barcoded and Pooled AAV Variants via Single-Cell RNA Sequencing", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-102237108", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200604-072416648, title = "Structure-Guided Rational Design of Adeno-Associated Viral Capsids with Expanded Sizes", journal = "Molecular Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-072416648", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200220-151529138, title = "LRP1 is a master regulator of tau uptake and spread", journal = "Nature", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200220-151529138", id = "record", issn = "0028-0836", doi = "10.1038/s41586-020-2156-5", volume = "580" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190220-102621411, title = "RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations", journal = "Nature Methods", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190220-102621411", id = "record", issn = "1548-7091", doi = "10.1038/s41592-020-0774-3", volume = "17", pmcid = "PMC7135964" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191209-154036633, title = "Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice", journal = "Nature Neuroscience", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191209-154036633", id = "record", issn = "1097-6256", doi = "10.1038/s41593-020-0589-7", volume = "23", pmcid = "PMC7065967" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200218-134259315, title = "A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice", journal = "eLife", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200218-134259315", id = "record", issn = "2050-084X", doi = "10.7554/elife.53111", volume = "9", pmcid = "PMC7012599" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200106-082556970, title = "Tissue clearing and its applications in neuroscience", journal = "Nature Reviews. Neuroscience", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200106-082556970", id = "record", issn = "1471-003X", doi = "10.1038/s41583-019-0250-1", volume = "21", pmcid = "PMC8121164" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191203-132507070, title = "Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue", journal = "Journal of Clinical Investigation", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191203-132507070", id = "record", issn = "0021-9738", doi = "10.1172/jci129167", volume = "130", pmcid = "PMC6934193" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190801-132221928, title = "Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators", journal = "Nature Protocols", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190801-132221928", id = "record", issn = "1754-2189", doi = "10.1038/s41596-019-0239-2", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191216-134424777, title = "Paracrine delivery of therapeutic biologics for cancer", journal = "Human Gene Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191216-134424777", id = "record", issn = "1043-0342", doi = "10.1089/hum.2019.29095.abstracts", volume = "30" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190304-085432637, title = "Machine learning-guided channelrhodopsin engineering enables minimally-invasive optogenetics", journal = "Nature Methods", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190304-085432637", id = "record", issn = "1548-7091", doi = "10.1038/s41592-019-0583-8", volume = "16", pmcid = "PMC6858556" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190930-133756080, title = "Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1", journal = "eLife", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190930-133756080", id = "record", issn = "2050-084X", doi = "10.7554/elife.48983", volume = "8", pmcid = "PMC6819083" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190926-135813898, title = "Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics", journal = "Frontiers in Neuroscience", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190926-135813898", id = "record", issn = "1662-453X", doi = "10.3389/fnins.2019.00936", volume = "13", pmcid = "PMC6751331" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191017-140230343, title = "Structural Studies of Engineered Adeno-Associated Virus Capsids that Cross Blood-Brain Barrier Efficiently", journal = "Protein Science", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191017-140230343", id = "record", issn = "0961-8368", doi = "10.1002/pro.3710", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190624-113552525, title = "The Serotonergic Raphe Promote Sleep in Zebrafish and Mice", journal = "Neuron", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190624-113552525", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2019.05.038", volume = "103", pmcid = "PMC6706304" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20181107-092306925, title = "Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies", journal = "Nature Communications", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20181107-092306925", id = "record", issn = "2041-1723", doi = "10.1038/s41467-019-09770-1", volume = "10", pmcid = "PMC6486614" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190503-152305499, title = "Multiplexed-CREATE Selection Yields AAV Vectors Targeting Different Cell Types of the Central Nervous System Following Systemic Delivery", journal = "Molecular Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190503-152305499", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2019.04.004", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190502-130505856, title = "Engineered AAVs for Enhanced Transduction of Submucosal Cells within the Lung Following Intravenous Delivery", journal = "Molecular Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190502-130505856", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2019.04.004", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190502-130921368, title = "Engineered AAVS for CNS Transduction and Peripheral Organ De-Targeting across Species after Systemic Delivery", journal = "Molecular Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190502-130921368", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2019.04.004", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190409-100816489, title = "TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice", journal = "Cell Reports", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190409-100816489", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2018.12.055", volume = "27", pmcid = "PMC6485958" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20190822-134054530, title = "High Contrast Metastructures VIII", chapter = "Double-wavelength metasurface objective lens for two-photon microscopy (Conference Presentation)", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190822-134054530", id = "record", isbn = "9781510624986", doi = "10.1117/12.2510596" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20190220-101926873, title = "Epigenetic landscape and AAV targeting of human neocortical cell classes", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190220-101926873", id = "record", doi = "10.1101/555318" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180816-125507808, title = "Systemic AAV vectors for widespread and targeted gene delivery in rodents", journal = "Nature Protocols", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180816-125507808", id = "record", issn = "1754-2189", doi = "10.1038/s41596-018-0097-3", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20181105-084438080, title = "Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy", journal = "Journal of Neuroscience", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20181105-084438080", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.1677-18.2018", volume = "38", pmcid = "PMC6706004" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180717-145659939, title = "Two-photon microscopy with a double-wavelength metasurface objective lens", journal = "Nano Letters", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180717-145659939", id = "record", issn = "1530-6984", doi = "10.1021/acs.nanolett.8b01737", volume = "18" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180507-085656725, title = "Viral Strategies for Targeting the Central and Peripheral Nervous Systems", journal = "Annual Review of Neuroscience", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180507-085656725", id = "record", issn = "0147-006X", doi = "10.1146/annurev-neuro-080317-062048", volume = "41" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180601-103720713, title = "Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors", journal = "Science", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180601-103720713", id = "record", issn = "0036-8075", doi = "10.1126/science.aat4422", volume = "360", pmcid = "PMC6287765" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180518-105323206, title = "The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress", journal = "Cell", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180518-105323206", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2018.03.037", volume = "173", pmcid = "PMC5967263" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180706-160530988, title = "Developing AAV Vectors for More Efficient and Selective Gene Expression in Specific Cell Types of the Nervous System Following Systemic Delivery", journal = "Molecular Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-160530988", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180529-083813817, title = "Hydrogel-Tissue Chemistry: Principles and Applications", journal = "Annual Review of Biophysics", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180529-083813817", id = "record", issn = "1936-122X", doi = "10.1146/annurev-biophys-070317-032905", volume = "47", pmcid = "PMC6359929" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180706-154255761, title = "Enhanced Efficacy of Gene Therapy Treatment for Niemann-Pick C1 Disease Using a Novel Serotype, AAV-PHP.B", journal = "Molecular Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-154255761", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180706-151207096, title = "Engineering Cell Type Specific Delivery Vectors for Noninvasive Modulation of Brain Circuits and Behaviors", journal = "Molecular Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-151207096", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20180711-103004538, title = "Adaptive Optics and Wavefront Control for Biological Systems IV", chapter = "Time-reversed ultrasonically encoded (TRUE) focusing for deep-tissue optogenetic modulation", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180711-103004538", id = "record", isbn = "9781510614895", doi = "10.1117/12.2288331" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170918-075519928, title = "Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research", journal = "Current Opinion in Neurobiology", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170918-075519928", id = "record", issn = "0959-4388", doi = "10.1016/j.conb.2017.08.003", volume = "48", pmcid = "PMC5825239" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180301-095437009, title = "Gene therapy for the treatment of Niemann-Pick disease type C1: Comparison of AAV9 to a novel serotype, AAV-PHP.B", journal = "Molecular Genetics and Metabolism", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180301-095437009", id = "record", issn = "1096-7192", doi = "10.1016/j.ymgme.2017.12.075", volume = "123" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171107-132336726, title = "Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light", journal = "Science Advances", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171107-132336726", id = "record", issn = "2375-2548", doi = "10.1126/sciadv.aao5520", volume = "3", pmcid = "PMC5722648" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180108-144650592, title = "Bone CLARITY reveals that anti-sclerostin antibody penetrates the lacunar canalicular system in mice under physiological loading conditions", journal = "Journal of Bone and Mineral Research", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180108-144650592", id = "record", issn = "0884-0431", doi = "10.1002/jbmr.3363", volume = "32" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171127-142458372, title = "Overriding sleep", journal = "Science", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171127-142458372", id = "record", issn = "0036-8075", doi = "10.1126/science.aap9535", volume = "358" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171030-140148566, title = "Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization", journal = "PLOS Computational Biology", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171030-140148566", id = "record", issn = "1553-7358", doi = "10.1371/journal.pcbi.1005786", volume = "13", pmcid = "PMC5695628" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170921-075913502, title = "The Jellyfish Cassiopea Exhibits a Sleep-like State", journal = "Current Biology", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170921-075913502", id = "record", issn = "0960-9822", doi = "10.1016/j.cub.2017.08.014", volume = "27", pmcid = "PMC5653286" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170926-130537624, title = "Q\&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology?", journal = "BMC Biology", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170926-130537624", id = "record", issn = "1741-7007", doi = "10.1186/s12915-017-0421-3", volume = "15", pmcid = "PMC5613628" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170626-152125765, title = "Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems", journal = "Nature Neuroscience", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170626-152125765", id = "record", issn = "1097-6256", doi = "10.1038/nn.4593", volume = "20", pmcid = "PMC5529245" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170609-094413808, title = "Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli", journal = "Neuron", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170609-094413808", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2017.05.020", volume = "94" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170522-103736207, title = "Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex", journal = "Neuron", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170522-103736207", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2017.04.017", volume = "94", pmcid = "PMC5723385" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170601-080728015, title = "Adeno-Associated Viral Gene Therapy Using PHP.B:NPC1 Ameliorates Disease Phenotype in Mouse Model of Niemann-Pick C1 Disease", journal = "Molecular Therapy", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170601-080728015", id = "record", issn = "1525-0016", doi = "10.1016/j.ymthe.2017.04.025", volume = "25" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20161221-135116035, title = "Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow", journal = "Science Translational Medicine", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161221-135116035", id = "record", issn = "1946-6234", doi = "10.1126/scitranslmed.aah6518", volume = "9" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170310-130542741, title = "Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170310-130542741", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1700269114", volume = "114", pmcid = "PMC5380088" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170307-082231020, title = "Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore", journal = "Cell Chemical Biology", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170307-082231020", id = "record", issn = "2451-9456", doi = "10.1016/j.chembiol.2017.02.008", volume = "24", pmcid = "PMC5357175" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20161115-114016210, title = "Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease", journal = "Cell", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161115-114016210", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2016.11.018", volume = "167", pmcid = "PMC5718049" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20161128-093036959, title = "Global Collaboration, Learning from Other Fields", journal = "Neuron", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161128-093036959", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2016.10.040", volume = "92" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160920-092113773, title = "Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation", journal = "Nature Cell Biology", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160920-092113773", id = "record", issn = "1465-7392", doi = "10.1038/ncb3410", volume = "18", pmcid = "PMC5536113" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160927-144217261, title = "Exposing the Three-Dimensional Biogeography and Metabolic States of Pathogens in Cystic Fibrosis Sputum via Hydrogel Embedding, Clearing, and rRNA Labeling", journal = "mBio", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160927-144217261", id = "record", issn = "2150-7511", doi = "10.1128/mBio.00796-16", volume = "7", pmcid = "PMC5040109" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160628-085406782, title = "Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing", journal = "Development", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160628-085406782", id = "record", issn = "0950-1991", doi = "10.1242/dev.138560", volume = "143", pmcid = "PMC5004914" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160712-101339180, title = "Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors", journal = "Current Opinion in Biotechnology", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160712-101339180", id = "record", issn = "0958-1669", doi = "10.1016/j.copbio.2016.03.012", volume = "40", pmcid = "PMC4975678" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160527-092723542, title = "Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System", journal = "Molecular Therapy", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160527-092723542", id = "record", issn = "1525-0016", doi = "10.1016/S1525-0016(16)33061-1", volume = "24" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160420-090626768, title = "Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways", journal = "Neuron", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160420-090626768", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2016.03.028", volume = "90", pmcid = "PMC4840478" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160606-133730058, title = "Tools for Anatomical and Functional Analysis of Widely Distributed Brain Networks", journal = "Biophysical Journal", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160606-133730058", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.1965", volume = "110" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160603-153016574, title = "Rhodopsin Engineering through Structure-Guided Recombination", journal = "Biophysical Journal", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160603-153016574", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.947", volume = "110" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160201-131537838, title = "Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain", journal = "Nature Biotechnology", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160201-131537838", id = "record", issn = "1087-0156", doi = "10.1038/nbt.3440", volume = "34", pmcid = "PMC5088052" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160202-092152118, title = "Fluorescent boost for voltage sensors", journal = "Nature", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160202-092152118", id = "record", issn = "0028-0836", doi = "10.1038/529469a", volume = "529" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160108-103050704, title = "Genomic Reconstruction of an Uncultured Hydrothermal Vent Gammaproteobacterial Methanotroph (Family Methylothermaceae) Indicates Multiple Adaptations to Oxygen Limitation", journal = "Frontiers in Microbiology", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160108-103050704", id = "record", issn = "1664-302X", doi = "10.3389/fmicb.2015.01425", volume = "6", pmcid = "PMC4688376" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150914-123933415, title = "Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping", journal = "Nature Protocols", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150914-123933415", id = "record", issn = "1754-2189", doi = "10.1038/nprot.2015.122", volume = "10", pmcid = "PMC4917295" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150728-090618874, title = "Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo", journal = "Chemistry and Biology", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150728-090618874", id = "record", issn = "1074-5521", doi = "10.1016/j.chembiol.2015.06.020", volume = "22", pmcid = "PMC4546540" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140730-113211664, title = "Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons", journal = "Nature Communications", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140730-113211664", id = "record", issn = "2041-1723", doi = "10.1038/ncomms5894", volume = "5", pmcid = "PMC4166526" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140825-213535516, title = "Directed evolution of a far-red fluorescent rhodopsin", journal = "Proceedings of the National Academy of Sciences of the United States of America", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140825-213535516", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1413987111", volume = "111", pmcid = "PMC4246972" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140801-121634734, title = "Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing", journal = "Cell", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140801-121634734", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2014.07.017", volume = "158", pmcid = "PMC4153367" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140714-121054059, title = "Bioelectronic medicines: a research roadmap", journal = "Nature Reviews Drug Discovery", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140714-121054059", id = "record", issn = "1474-1776", doi = "10.1038/nrd4351", volume = "13" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130513-151857819, title = "Structural and molecular interrogation of intact biological systems", journal = "Nature", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130513-151857819", id = "record", issn = "0028-0836", doi = "10.1038/nature12107", volume = "497", pmcid = "PMC4092167" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130513-151856843, title = "Optogenetic Delay of Status Epilepticus Onset in an In Vivo Rodent Epilepsy Model", journal = "PLoS ONE", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130513-151856843", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0062013", volume = "8", pmcid = "PMC3634849" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-140040487, title = "Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins", journal = "Nature Methods", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-140040487", id = "record", issn = "1548-7091", doi = "10.1038/NMETH.1808", volume = "9", pmcid = "PMC4165888" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-152726999, title = "Leptin regulates the reward value of nutrient", journal = "Nature Neuroscience", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-152726999", id = "record", issn = "1097-6256", doi = "10.1038/nn.2977", volume = "14", pmcid = "PMC4238286" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-085452439, title = "Dynamics of Retrieval Strategies for Remote Memories", journal = "Cell", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-085452439", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2011.09.033", volume = "147" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-133910388, title = "Amygdala circuitry mediating reversible and bidirectional control of anxiety", journal = "Nature", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-133910388", id = "record", issn = "0028-0836", doi = "10.1038/nature09820", volume = "471", pmcid = "PMC3154022" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121211-085000915, title = "Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning", journal = "Science", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121211-085000915", id = "record", issn = "0036-8075", doi = "10.1126/science.1193771", volume = "330", pmcid = "PMC3142356" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-103459856, title = "Global and local fMRI signals driven by neurons defined optogenetically by type and wiring", journal = "Nature", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-103459856", id = "record", issn = "0028-0836", doi = "10.1038/nature09108", volume = "465", pmcid = "PMC3177305" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-083746393, title = "Molecular and Cellular Approaches for Diversifying and Extending Optogenetics", journal = "Cell", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-083746393", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2010.02.037", volume = "141", pmcid = "PMC4160532" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-154946294, title = "Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures", journal = "Nature Protocols", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-154946294", id = "record", issn = "1754-2189", doi = "10.1038/nprot.2009.226", volume = "5", pmcid = "PMC4503465" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121211-083527990, title = "Optical Deconstruction of Parkinsonian Neural Circuitry", journal = "Science", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121211-083527990", id = "record", issn = "0036-8075", doi = "10.1126/science.1167093", volume = "324", pmcid = "PMC6744370" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-102214115, title = "eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications", journal = "Brain Cell Biology", year = "2008", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-102214115", id = "record", issn = "1559-7105", doi = "10.1007/s11068-008-9027-6", volume = "36", pmcid = "PMC2588488" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-101209730, title = "Controlling Neuronal Activity", journal = "American Journal of Psychiatry", year = "2008", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-101209730", id = "record", issn = "0002-953X", doi = "10.1176/appi.ajp.2008.08030444", volume = "165" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121206-095456619, title = "Targeting and Readout Strategies for Fast Optical Neural Control In Vitro and In Vivo", journal = "Journal of Neuroscience", year = "2007", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-095456619", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.3578-07.2007", volume = "27", pmcid = "PMC6673457" }