Kumagai, Akiko

Combined from CaltechAUTHORS

• Haccard, Olivier and Ciardo, Diletta, el al. (2023) Rif1 restrains the rate of replication origin firing in Xenopus laevis; Communications Biology; Vol. 6; 788; PMCID PMC10387115; 10.1038/s42003-023-05172-8
• Kumagai, Akiko and Dunphy, William G. (2020) Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication; Cell Reports; Vol. 32; No. 12; Art. No. 108178; PMCID PMC7523632; 10.1016/j.celrep.2020.108178
• Lim, Daniel C. and Joukov, Vladimir, el al. (2020) Redox priming promotes Aurora A activation during mitosis; Science Signaling; Vol. 13; No. 641; Art. No. eabb6707; PMCID PMC8514121; 10.1126/scisignal.abb6707
• Lyu, Ke and Kumagai, Akiko, el al. (2019) RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR; Cell Cycle; Vol. 18; No. 8; 898-913; 10.1080/15384101.2019.1598728
• Kumagai, Akiko and Dunphy, William G. (2017) MTBP, the Partner of Treslin, Contains a Novel DNA-Binding Domain, That Is Essential for Proper Initiation of DNA Replication; Molecular Biology of the Cell; Vol. 28; No. 22; 2998-3012; PMCID PMC5662258; 10.1091/mbc.E17-07-0448
• Mu, Ruiling and Tat, John, el al. (2017) CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin; Molecular and Cellular Biology; Vol. 37; No. 20; Art. No. e00344; PMCID PMC5615187; 10.1128/MCB.00344-17
• Ryu, Hyunju and Yoshida, Makoto M., el al. (2015) SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin; Cell Cycle; Vol. 14; No. 17; 2777-2784; PMCID PMC4614044; 10.1080/15384101.2015.1066537
• Guo, Cai and Kumagai, Akiko, el al. (2015) Interaction of Chk1 with Treslin Negatively Regulates the Initiation of Chromosomal DNA Replication; Molecular Cell; Vol. 57; No. 3; 492-505; PMCID PMC4321788; 10.1016/j.molcel.2014.12.003
• Kumar, Sanjay and Yoo, Hae Yong, el al. (2012) Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts; Cell Cycle; Vol. 11; No. 6; 1183-1194; 10.4161/cc.11.6.19636
• Kumagai, Akiko and Shevchenko, Anna, el al. (2011) Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication; Journal of Cell Biology; Vol. 193; No. 6; 995-1007; PMCID PMC3115804; 10.1083/jcb.201102003
• Kumagai, Akiko and Shevchenko, Anna, el al. (2010) Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication; Cell; Vol. 140; No. 3; 349-359; 10.1016/j.cell.2009.12.049
• Yoo, Hae Yong and Kumagai, Akiko, el al. (2009) The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM; Molecular Biology of the Cell; Vol. 20; No. 9; 2351-2360; PMCID PMC2675615; 10.1091/mbc.E08-12-1190
• Lee, Joon and Kumagai, Akiko, el al. (2007) The Rad9-Hus1-Rad1 Checkpoint Clamp Regulates Interaction of TopBP1 with ATR; Journal of Biological Chemistry; Vol. 282; No. 38; 28036-28044; 10.1074/jbc.M704635200
• Yoo, Hae Yong and Kumagai, Akiko, el al. (2007) Ataxia-telangiectasia Mutated (ATM)-dependent Activation of ATR Occurs through Phosphorylation of TopBP1 by ATM; Journal of Biological Chemistry; Vol. 282; No. 24; 17501-17506; 10.1074/jbc.M701770200
• Kim, Soon-Mi and Kumagai, Akiko, el al. (2005) Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus Egg Extracts Requires Binding of ATRIP to ATR but Not the Stable DNA-binding or Coiled-coil Domains of ATRIP; Journal of Biological Chemistry; Vol. 280; No. 46; 38355-38364; 10.1074/jbc.M508673200
• Kumagai, Akiko and Kim, Soo-Mi, el al. (2004) Claspin and the Activated Form of ATR-ATRIP Collaborate in the Activation of Chk1; Journal of Biological Chemistry; Vol. 279; No. 48; 49599-49608; 10.1074/jbc.M408353200
• Jeong, Seong-Yun and Kumagai, Akiko, el al. (2003) Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation; Journal of Biological Chemistry; Vol. 278; No. 47; 46782-46788; 10.1074/jbc.M304551200
• Kumagai, Akiko and Dunphy, William G. (2003) Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1; Nature Cell Biology; Vol. 5; No. 2; 161-165; 10.1038/ncb921
• Sakamoto, Kathleen M. and Kim, Kyung B., el al. (2001) Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation; Proceedings of the National Academy of Sciences of the United States of America; Vol. 98; No. 15; 8554-8559; PMCID PMC37474; 10.1073/pnas.141230798
• Budde, Priya Prakash and Kumagai, Akiko, el al. (2001) Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts; Journal of Cell Biology; Vol. 153; No. 1; 149-157; 10.1083/jcb.153.1.149
• Lee, Joon and Kumagai, Akiko, el al. (2001) Positive regulation of Wee1 by Chk1 and 14-3-3 proteins; Molecular Biology of the Cell; Vol. 12; No. 3; 551-563; PMCID PMC30963; 10.1091/mbc.12.3.551
• Patra, Debabrata and Wang, Sophie X., el al. (1999) The Xenopus Suc1/Cks Protein Promotes the Phosphorylation of G2/M Regulators; Journal of Biological Chemistry; Vol. 274; No. 52; 36839-36842
• Kumagai, Akiko and Guo, Zijian, el al. (1998) The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts; Journal of Cell Biology; Vol. 142; No. 6; 1559-1569; PMCID PMC2141764; 10.1083/jcb.142.6.1559
• Kumagai, Akiko and Yakowec, Peter S., el al. (1998) 14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 in Xenopus Egg Extracts; Molecular Biology of the Cell; Vol. 9; No. 2; 345-354; PMCID PMC25261
• Kumagai, Akiko and Dunphy, William G. (1996) Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts; Science; Vol. 273; No. 5280; 1377-1380; 10.1126/science.273.5280.1377
• Mueller, Paul R. and Coleman, Thomas R., el al. (1995) Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15; Science; Vol. 270; No. 5233; 86-90; 10.1126/science.270.5233.86
• Kumagai, Akiko and Dunphy, William G. (1995) Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors; Molecular Biology of the Cell; Vol. 6; No. 2; 199-213; PMCID PMC275829