Ondrus, Alison E.

Combined from CaltechAUTHORS

• Vo, Amy-Doan P. and Kim, Soo-Kyung, et el. (2023) Fully activated structure of the sterol-bound Smoothened GPCR-Gi protein complex; Proceedings of the National Academy of Sciences; Vol. 120; No. 49; e2300919120; PMCID PMC10710022; 10.1073/pnas.2300919120
• Mendoza, Manuel and Tran, UyenPhuong, et el. (2022) Indolactam Dipeptides as Nanomolar Gli Inhibitors; ACS Medicinal Chemistry Letters; Vol. 13; No. 7; 1036-1042; PMCID PMC9290001; 10.1021/acsmedchemlett.1c00562
• Feng, Zhiping and Hom, Marisa E., et el. (2022) Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1; Nature Chemical Biology; Vol. 18; 1065-1075; 10.1038/s41589-022-01048-w
• Cheng, Yu-Shiuan and Zhang, Tianyi, et el. (2021) A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes; Nature Chemical Biology; Vol. 17; No. 12; 1271-1280; PMCID PMC8607797; 10.1038/s41589-021-00907-2
• Zhang, Tianyi and Ondrus, Alison E. (2021) Structure, Bonding, and Photoaffinity Labeling Applications of Dialkyldiazirines; Synlett; Vol. 32; No. 11; 1053-1059; 10.1055/a-1437-8202
• Mafi, Amirhossein and Purohit, Rahul, et el. (2021) Hedgehog proteins create a dynamic cholesterol interface; PLoS ONE; Vol. 16; No. 2; Art. No. e0246814; 10.1371/journal.pone.0246814
• Tran, UyenPhuong and Zhang, Grace C., et el. (2020) Small Molecule Intervention in a Protein Kinase C–Gli Transcription Factor Axis; ACS Chemical Biology; Vol. 15; No. 6; 1321-1327; PMCID PMC8842554; 10.1021/acschembio.0c00355
• Hom, Marisa E. and Ondrus, Alison E., et el. (2020) Bicyclic imidazolium inhibitors of Gli transcription factor activity; ChemMedChem; Vol. 15; No. 12; 1044-1049; PMCID PMC7311267; 10.1002/cmdc.202000169
• Purohit, Rahul and Peng, Daniel S., et el. (2020) Dual roles of the Sterol Recognition Region in Hedgehog protein modification; Communications Biology; Vol. 3; Art. No. 250; PMCID PMC7242414; 10.1038/s42003-020-0977-2
• Purohit, Rahul and Vielmas, Erika, et el. (2020) Defining roles of the sterol recognition region in Hedgehog cholesterolyation; FASEB Journal; Vol. 34; No. S1; 1; 10.1096/fasebj.2020.34.s1.09381
• Purohit, Rahul and Vielmas, Erika, et el. (2020) Defining roles of the sterol recognition region in Hedgehog cholesterolyation; FASEB Journal; Vol. 34; No. S1; 1; 10.1096/fasebj.2020.34.s1.09381
• Ondrus, Alison E. (2019) Mapping the oxysterol interactome
• Ondrus, Alison Evelynn and Movassaghi, Mohammad (2017) Total synthesis and study of myrmicarin alkaloids
• Steinman, Jonathan B. and Santarossa, Cristina C., et el. (2017) Chemical structure-guided design of dynapyrazoles, potent cell-permeable dynein inhibitors with a unique mode of action; eLife; Vol. 6; Art. No. e25174; PMCID PMC5478271; 10.7554/eLife.25174
• Chen, James and Kato, Tomoyo Sakata, et el. (2014) Imidazo bibyclic imminium compounds as antitumor agents
• Ondrus, Alison E. and Lee, Hsiao-lu D., et el. (2012) Fluorescent Saxitoxins for Live Cell Imaging of Single Voltage-Gated Sodium Ion Channels beyond the Optical Diffraction Limit; Chemistry and Biology; Vol. 19; No. 7; 902-912; PMCID PMC3731772; 10.1016/j.chembiol.2012.05.021
• Ondrus, Alison E. and Ümit Kaniskan, H., et el. (2010) Dimerization of functional pyrroloindolizines for the synthesis of complex myrmicarin alkaloids; Tetrahedron; Vol. 66; No. 26; 4784-4795; PMCID PMC2925304; 10.1016/j.tet.2010.04.006
• Ondrus, Alison E. and Movassaghi, Mohammad (2009) Total synthesis and study of myrmicarin alkaloids; Chemical Communications; Vol. 2009; No. 28; 4151-4165; PMCID PMC2987668; 10.1039/b903995n
• Ondrus, Alison E. and Movassaghi, Mohammad (2009) Reversible Dimerization of (+)-Myrmicarin 215B; Organic Letters; Vol. 11; No. 14; 2960-2963; PMCID PMC2752850; 10.1021/ol9008552
• Guggenheim, Evan R. and Ondrus, Alison E., et el. (2008) Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA; Bioorganic and Medicinal Chemistry; Vol. 16; No. 23; 10121-10128; PMCID PMC2662712; 10.1016/j.bmc.2008.09.074
• Movassaghi, Mohammad and Ondrus, Alison E., et el. (2007) Efficient and Stereoselective Dimerization of Pyrroloindolizine Derivatives Inspired by a Hypothesis for the Biosynthesis of Complex Myrmicarin Alkaloids; Journal of Organic Chemistry; Vol. 72; No. 26; 10065-10074; PMCID PMC2992888; 10.1021/jo701981q
• Ondrus, Alison E. and Movassaghi, Mohammad (2006) Dimerization of (+)-myrmicarin 215B. A potential biomimetic approach to complex myrmicarin alkaloids; Tetrahedron; Vol. 62; No. 22; 5287-5297; PMCID PMC2904612; 10.1016/j.tet.2006.01.108
• Movassaghi, Mohammad and Ondrus, Alison E. (2005) Palladium-Catalyzed Synthesis of N-Vinyl Pyrroles and Indoles; Journal of Organic Chemistry; Vol. 70; No. 21; 8638-8641; PMCID PMC5548004; 10.1021/jo051450i
• Movassaghi, Mohammad and Ondrus, Alison E. (2005) Enantioselective Total Synthesis of Tricyclic Myrmicarin Alkaloids; Organic Letters; Vol. 7; No. 20; 4423-4426; PMCID PMC2992882; 10.1021/ol051629f