[
    {
        "id": "authors:a4fa0-tnp50",
        "collection": "authors",
        "collection_id": "a4fa0-tnp50",
        "cite_using_url": "https://authors.library.caltech.edu/records/a4fa0-tnp50",
        "type": "article",
        "title": "Enantioselective Synthesis of (+)-Auriculatol A",
        "author": [
            {
                "family_name": "Thompson",
                "given_name": "Jordan K.",
                "orcid": "0009-0007-6395-7087",
                "clpid": "Thompson-Jordan-Kenji"
            },
            {
                "family_name": "Youngblood",
                "given_name": "Kala C.",
                "orcid": "0000-0002-4686-1979",
                "clpid": "Youngblood-Kala-C"
            },
            {
                "family_name": "Teh",
                "given_name": "Yun Hao Shawn",
                "orcid": "0009-0005-4981-7841",
                "clpid": "Teh-Yun-Hao-Shawn"
            },
            {
                "family_name": "Farley",
                "given_name": "Conner M.",
                "orcid": "0000-0002-4067-0848",
                "clpid": "Farley-Conner-M"
            },
            {
                "family_name": "Zhang",
                "given_name": "Zhehao",
                "orcid": "0009-0008-7893-1274",
                "clpid": "Zhang-Zhehao"
            },
            {
                "family_name": "Virgil",
                "given_name": "Scott C.",
                "orcid": "0000-0001-8586-5641",
                "clpid": "VIrgil-S-C"
            },
            {
                "family_name": "Reisman",
                "given_name": "Sarah E.",
                "orcid": "0000-0001-8244-9300",
                "clpid": "Reisman-S-E"
            }
        ],
        "abstract": "A total synthesis of the grayanane diterpenoid (+)-auriculatol A is reported. The synthesis features a convergent coupling strategy that joins two fragments by a vinylogous Mukaiyama-aldol-type reaction and then constructs the 7-membered ring by a Ni-catalyzed enolate alkenylation. Key findings include the development of a chemoselective Ni-catalyzed intramolecular 1,2-addition to access the bicyclo[3.2.1]octane fragment and the use of electron-deficient olefin supporting ligands as uniquely effective for the Ni-catalyzed enolate alkenylation.",
        "doi": "10.1021/jacs.5c17269",
        "pmcid": "PMC12636016",
        "issn": "0002-7863",
        "publisher": "American Chemical Society",
        "publication": "Journal of the American Chemical Society",
        "publication_date": "2025-11-19",
        "series_number": "46",
        "volume": "147",
        "issue": "46",
        "pages": "42170\u201342174"
    }
]